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斑秃中的性功能障碍:一项系统评价。

Sexual Dysfunction in Alopecia Areata: A Systematic Review.

作者信息

Krajewski Piotr K, Złotowska Aleksandra, Szepietowski Jacek C, Saceda Corralo David

机构信息

University Centre of General Dermatology and Oncodermatology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

Department of Dermatovenereology, 4th Military Hospital, 50-981 Wroclaw, Poland.

出版信息

J Clin Med. 2025 Apr 10;14(8):2602. doi: 10.3390/jcm14082602.

DOI:10.3390/jcm14082602
PMID:40283432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12027524/
Abstract

Alopecia areata (AA) contributes to clinically significant suffering, and impaired social functioning. Among AA patients, there is a clear impact of the disease on their sense of attractiveness and desirability as sexual partners. This review explores the development of sexual disorders among AA patients, highlighting their importance in the clinical diagnosis of comorbid health disorders with hair loss. A systematic review was conducted by searching electronic databases, including MEDLINE and Google Scholar, without date limitations, according to the PRISMA guidelines. Key search terms included "sexuality" or "sexual health" or "sexual dysfunction" or "sexual disorder" AND "alopecia areata". Data synthesis included findings from eight relevant studies. Hair loss in the course of AA has a negative impact on the sexual sphere, significantly reducing the quality of life of patients and their partners. Proper sexual functioning is an integral part of every person, so special attention should be paid to the possibility of developing sexual dysfunction in the course of AA. Small sample sizes and heterogeneous populations make it difficult to draw firm conclusions. Continued research with standardized criteria for SD diagnosis and appropriately large cohorts will be essential to fully establish psychosexual disorders among AA patients.

摘要

斑秃(AA)会导致临床上显著的痛苦和社会功能受损。在斑秃患者中,该疾病对他们作为性伴侣的吸引力和受欢迎程度有明显影响。本综述探讨了斑秃患者性功能障碍的发展情况,强调了其在伴有脱发的共病健康障碍临床诊断中的重要性。根据PRISMA指南,通过检索包括MEDLINE和谷歌学术在内的电子数据库进行了一项系统综述,检索无日期限制。关键检索词包括“性”或“性健康”或“性功能障碍”或“性障碍”以及“斑秃”。数据综合包括八项相关研究的结果。斑秃病程中的脱发对性方面有负面影响,显著降低了患者及其伴侣的生活质量。正常的性功能是每个人不可或缺的一部分,因此应特别关注斑秃病程中发生性功能障碍的可能性。样本量小和人群异质性使得难以得出确凿结论。采用标准化的性功能障碍诊断标准并进行适当大规模队列的持续研究对于全面确定斑秃患者的性心理障碍至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/093d/12027524/72daec18a12f/jcm-14-02602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/093d/12027524/c6228c82b84e/jcm-14-02602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/093d/12027524/72daec18a12f/jcm-14-02602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/093d/12027524/c6228c82b84e/jcm-14-02602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/093d/12027524/72daec18a12f/jcm-14-02602-g002.jpg

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本文引用的文献

1
Comparative study on sexual dysfunction in alopecia areata: prevalence and associated factors.斑秃患者性功能障碍的比较研究:患病率及相关因素
J Dtsch Dermatol Ges. 2024 Dec;22(12):1611-1618. doi: 10.1111/ddg.15527. Epub 2024 Oct 15.
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The psychosocial impact of alopecia in men: A mixed-methods survey study.男性脱发的社会心理影响:一项混合方法的调查研究。
Skin Health Dis. 2024 Jun 29;4(5):e420. doi: 10.1002/ski2.420. eCollection 2024 Oct.
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Psychosocial and mental impact of alopecia areata: Analysis of the Danish Skin Cohort.
斑秃的心理社会和精神影响:丹麦皮肤队列分析
J Eur Acad Dermatol Venereol. 2025 Mar;39(3):688-697. doi: 10.1111/jdv.20211. Epub 2024 Jun 28.
4
Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences.斑秃与白癜风的发病机制:共性与差异
Int J Mol Sci. 2024 Apr 17;25(8):4409. doi: 10.3390/ijms25084409.
5
Enhancing Quality of Life and Sexual Functioning in Female Androgenetic Alopecia: Therapeutic Potential of Hair Follicle-Derived Stem Cells.提高女性雄激素性脱发患者的生活质量和性功能:毛囊源性干细胞的治疗潜力
Healthcare (Basel). 2024 Mar 7;12(6):608. doi: 10.3390/healthcare12060608.
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Alopecia Areata: Current Treatments and New Directions.斑秃:现有治疗方法和新方向。
Am J Clin Dermatol. 2023 Nov;24(6):895-912. doi: 10.1007/s40257-023-00808-1. Epub 2023 Aug 22.
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The effectiveness of mindfulness-based cognitive therapy for social anxiety symptoms in people living with alopecia areata: a single-group case-series design.基于正念认知疗法对斑秃患者社交焦虑症状的疗效:单组病例系列设计。
Behav Cogn Psychother. 2023 Sep;51(5):381-395. doi: 10.1017/S1352465823000292. Epub 2023 Aug 8.
8
Janus kinase inhibitors for alopecia areata: A narrative review.Janus 激酶抑制剂治疗斑秃:综述。
Indian J Dermatol Venereol Leprol. 2023 Nov-Dec;89(6):799-806. doi: 10.25259/IJDVL_1093_2022.
9
Alopecia Areata: An Updated Review for 2023.斑秃:2023年最新综述
J Cutan Med Surg. 2023 May-Jun;27(3):241-259. doi: 10.1177/12034754231168839.
10
Sexual dysfunction related to psychiatric disorders: a systematic review.与精神障碍相关的性功能障碍:系统评价。
J Sex Med. 2023 Jun 28;20(7):965-976. doi: 10.1093/jsxmed/qdad074.