Combretastatin D系列及其类似物：从分离、合成挑战到生物活性
Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities.
作者信息
de Lima Neto Jorge, Menezes Paulo Henrique
机构信息
Universidade Federal de Pernambuco, Departamento de Química Fundamental, Recife-PE, 50740-560, Brazil.
出版信息
Beilstein J Org Chem. 2023 Mar 29;19:399-427. doi: 10.3762/bjoc.19.31. eCollection 2023.
Abstract
The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as the use of different strategies for their synthesis.
摘要
康布他汀D系列及其类似物、山茱萸内酯和异山茱萸内酯属于一类称为环状二芳基醚庚烷类（DAEH）的大环化合物。本综述旨在突出这些化合物的结构解析、生物合成和生物活性，以及合成它们的不同策略的应用。
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