Chihara J, Takebayashi S, Taguchi T, Yokoyama K, Harada T, Naito S
Nephron. 1986;43(1):45-9. doi: 10.1159/000183717.
Renal biopsies were obtained from 164 patients with diabetes mellitus. Their histological changes were evaluated together with clinical findings and prognosis. In 36 patients, various types of glomerulonephritis were complicated: mesangial proliferative glomerulonephritis (17 patients), membranous glomerulonephritis (8), endocapillary proliferative glomerulonephritis (5), membranoproliferative glomerulonephritis (4) and minimal change nephrotic syndrome (2). Superimposed glomerulonephritis was suspected in diabetic patients with a short history of less than 5 years, persistent proteinuria, occasional hematuria and no retinopathy. They may, however, produce little effects on the long-term prognosis of diabetic patients except membranoproliferative glomerulonephritis.
对164例糖尿病患者进行了肾活检。将其组织学变化与临床发现及预后进行了评估。36例患者合并了各种类型的肾小球肾炎：系膜增生性肾小球肾炎（17例）、膜性肾小球肾炎（8例）、毛细血管内增生性肾小球肾炎（5例）、膜增生性肾小球肾炎（4例）和微小病变肾病综合征（2例）。糖尿病病程短于5年、持续性蛋白尿、偶发血尿且无视网膜病变的患者疑似合并肾小球肾炎。然而，除膜增生性肾小球肾炎外，它们对糖尿病患者的长期预后可能影响不大。
