Department of Chemistry, University of North Bengal, Darjeeling, West Bengal, 734013, India.
Department of Chemistry, University of North Bengal, Darjeeling, West Bengal, 734013, India.
Anal Chim Acta. 2023 May 15;1255:341111. doi: 10.1016/j.aca.2023.341111. Epub 2023 Mar 21.
A benzoxazole-based fluorosensor (IMP) has been synthesized and employed for the selective and sensitive detection of sarin surrogate, diethylchlorophosphate (DCP) in solution, and gas phase, respectively. Remarkable turn-on fluorescence is observed due to the introduction of DCP in the solution of IMP because of inhibition of the intramolecular charge transfer process and disruption of the excited state intramolecular proton transfer (ESIPT) mechanism. The synthesized IMP-based fluorescence sensor exhibits excellent selectivity, high sensitivity, and a wide linear range of 15-60 μM with a detection limit of 44 nM. Low-intense to highly intensified visible violet color could be seen by the naked eye under a portable 365 nm UV lamp due to the addition of DCP in the solution of IMP. IMP-stained paper strips-based test kit experiment has been demonstrated to detect traces of DCP in stockpiles of related analytes. A dip-stick experiment for the detection of DCP vapor has also been demonstrated. The effectiveness of IMP in detecting DCP established that it might be used as a signal tool for real sample analysis.
已合成了一种基于苯并恶唑的荧光传感器（IMP），并分别用于溶液相和气相中沙林替代品二乙基氯膦（DCP）的选择性和灵敏检测。由于 DCP 的引入，抑制了分子内电荷转移过程并破坏了激发态分子内质子转移（ESIPT）机制，因此在 IMP 的溶液中观察到显著的荧光开启。基于合成的 IMP 的荧光传感器表现出优异的选择性、高灵敏度和 15-60 μM 的宽线性范围，检测限低至 44 nM。由于在 IMP 的溶液中添加了 DCP，因此可以通过肉眼在便携式 365nm UV 灯下看到从低强度到高强度的可见紫色颜色。已经证明了基于 IMP 染色纸条的测试套件实验可用于检测相关分析物库存中的 DCP 痕迹。还已经证明了用于检测 DCP 蒸气的浸棒实验。IMP 检测 DCP 的有效性表明它可被用作实际样品分析的信号工具。
