Wang Lina, Ma Ning, Wei Linlin
Department of Neurology, Xi'an Ninth Hospital Affiliated to Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, 710052, China.
Core Research Laboratory, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China.
Nutr Metab Cardiovasc Dis. 2023 Jun;33(6):1190-1196. doi: 10.1016/j.numecd.2023.03.009. Epub 2023 Mar 21.
Excessive sugar-sweetened beverages (SSBs) intake is associated with a higher risk of ischemic heart disease (IHD). However, global patterns and trends in the burden of IHD attributable to high SSBs intake have not been systematically assessed.
We retrieved data from the Global Burden of Disease Study (GBD) 2019. We obtained the numbers and age-standardized mortality rate (ASMR) and disability-adjusted life years (DALYs) rate (ASDR) of IHD attributable to high SSBs intake by sex, year, socio-demographic index (SDI), and country between 1990 and 2019. Furthermore, we used a validated decomposition algorithm to attribute changes to population growth, population aging, and epidemiologic changes in the 21 GBD regions. From 1990 to 2019, the global IHD mortality attributable to high SSBs intake, as quantified by ASMR and ASDR declined significantly, while the burden increased saliently in absolute numbers. Population decomposition suggested that changes in epidemiology in most GBD regions have reduced IHD mortality due to high SSBs intake, but this trend has been counteracted by population growth and aging.
Although the age-standardized rate of IHD deaths and DALYs attributable to high SSBs intake decreased overall from 1990 to 2019, the absolute IHD burden remains high in some countries, especially in some developing countries in Asia and Oceania. Action is needed to enhance the prevention of diseases associated with high SSBs intake.
过量摄入含糖饮料(SSB)与缺血性心脏病(IHD)风险升高有关。然而,全球因高糖饮料摄入量导致的缺血性心脏病负担的模式和趋势尚未得到系统评估。
我们从《2019年全球疾病负担研究》(GBD)中检索数据。我们获取了1990年至2019年间按性别、年份、社会人口指数(SDI)和国家划分的因高糖饮料摄入量导致的缺血性心脏病的病例数、年龄标准化死亡率(ASMR)和伤残调整生命年(DALY)率(ASDR)。此外,我们使用经过验证的分解算法来确定21个GBD区域中人口增长、人口老龄化和流行病学变化所导致的变化。从1990年到2019年,通过ASMR和ASDR量化的因高糖饮料摄入量导致的全球缺血性心脏病死亡率显著下降,而绝对负担则显著增加。人口分解表明,大多数GBD区域的流行病学变化降低了因高糖饮料摄入量导致的缺血性心脏病死亡率,但这一趋势被人口增长和老龄化所抵消。
尽管从1990年到2019年,因高糖饮料摄入量导致的缺血性心脏病死亡和伤残调整生命年的年龄标准化率总体下降,但在一些国家,尤其是亚洲和大洋洲的一些发展中国家,缺血性心脏病的绝对负担仍然很高。需要采取行动加强对与高糖饮料摄入量相关疾病的预防。