全球、区域和国家归因于 1990 年至 2019 年环境 PM 导致的缺血性心脏病负担：2019 年全球疾病负担研究分析。
Global, regional, and national burden of ischemic heart disease attributable to ambient PM from 1990 to 2019: An analysis for the global burden of disease study 2019.
机构信息
Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou, 510655, China.
出版信息
Environ Res. 2024 Jan 15;241:117635. doi: 10.1016/j.envres.2023.117635. Epub 2023 Nov 14.
Information on the spatio-temporal patterns of the burden of ischemic heart disease (IHD) caused by ambient ambient fine particulate matter (PM) in the global level is needed to prioritize the control of ambient air pollution and prevent the burden of IHD. The Global Burden of Disease Study (GBD) 2019 provides data on IHD attributable to ambient PM. The IHD burden and mortality attributable to ambient PM were analyzed by year, age, gender, socio-demographic index (SDI) level, geographical region and country. Estimated annual percentage change (EAPC) was calculated to estimate the temporal trends of age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years rate (ASDR) from 1990 to 2019. Globally, the ASMR and ASDR for ambient PM-related IHD tended to level off generally, with EAPC of -0.03 (95% CI: -0.06, 0.12) and 0.3 (95% CI: 0.22, 0.37), respectively. In the past 30 years, there were obvious differences in the trend of burden change among different regions. A highest increased burden was estimated in low-middle SDI region (EAPC of ASMR: 3.73 [95% CI: 3.56, 3.9], EAPC of ASDR: 3.83 [95% CI: 3.64, 4.02]). In contrast, the burden in high SDI region (EAPC of ASMR: -4.48 [95% CI: -4.6, -4.35], EAPC of ASDR: -3.98 [95% CI: -4.12, -3.85]) has declined most significantly. Moreover, this burden was higher among men and older populations. EAPCs of the ASMR (R = -0.776, p < 0.001) and ASDR (R = -0.781, p < 0.001) of this burden had significant negative correlations with the countries' SDI level. In summary, although trends in the global burden of IHD attributable to ambient PM are stabilizing, but this burden has shifted from high SDI countries to middle and low SDI countries, especially among men and elderly populations. To reduce this burden, the air pollution management prevention need to be further strengthened, especially among males, older populations, and middle and low SDI countries.
在全球范围内，需要了解环境细颗粒物（PM）引起的缺血性心脏病（IHD）负担的时空模式信息，以便优先控制环境空气污染并预防 IHD 负担。2019 年全球疾病负担研究（GBD）提供了归因于环境 PM 的 IHD 数据。分析了环境 PM 造成的 IHD 负担和死亡率按年份、年龄、性别、社会人口指数（SDI）水平、地理区域和国家分布。计算了估计年百分比变化（EAPC），以估计 1990 年至 2019 年年龄标准化死亡率（ASMR）和年龄标准化伤残调整生命年率（ASDR）的时间趋势。总的来说，全球与环境 PM 相关的 IHD 的 ASMR 和 ASDR 趋于平稳，EAPC 分别为-0.03（95%CI：-0.06，0.12）和 0.3（95%CI：0.22，0.37）。在过去的 30 年中，不同地区的负担变化趋势存在明显差异。中低 SDI 地区的负担增加幅度估计最高（ASMR 的 EAPC：3.73 [95%CI：3.56，3.9]，ASDR 的 EAPC：3.83 [95%CI：3.64，4.02]）。相比之下，高 SDI 地区的负担（ASMR 的 EAPC：-4.48 [95%CI：-4.6，-4.35]，ASDR 的 EAPC：-3.98 [95%CI：-4.12，-3.85]）下降幅度最大。此外，这种负担在男性和老年人群中更高。该负担的 ASMR（R=−0.776，p<0.001）和 ASDR（R=−0.781，p<0.001）的 EAPC 与各国 SDI 水平呈显著负相关。总之，尽管归因于环境 PM 的 IHD 全球负担呈稳定趋势，但负担已从中高 SDI 国家转移到中低 SDI 国家，特别是在男性和老年人群中。为了降低这种负担，需要进一步加强空气污染管理预防，特别是在男性、老年人群和中低 SDI 国家。
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