Fan Jinsong
National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Environ Sci Pollut Res Int. 2023 Nov;30(53):114514-114524. doi: 10.1007/s11356-023-30336-8. Epub 2023 Oct 20.
Elevated risk of ischemic heart disease (IHD) is associated with exposure to fine particulate matter. However, there is limited data on trends and comparisons in the global burden of IHD due to household air pollution from solid fuels (HAP) and ambient particulate matter pollution (APMP), particularly in regions of varying socio-economic levels. Based on the Global Burden of Disease Study 2019 (GBD 2019), we obtained age-standardized mortality rates (ASMR) and age-standardized disability-adjusted life years (ASDR) of IHD due to APMP and HAP from 1990 to 2019. Trends in the burden of IHD attributable to APMP and HAP during the period 1990 to 2019 were calculated by Joinpoint models. We estimated the relationship between ASMR with the socio-demographic indexes (SDI) and the health care accessibility and quality (HAQ) index by the Loess regression model. In 2019, the global burden of IHD ASMR attributed to APMP stabilized, but the most significant increases were observed in low-middle SDI regions. The global IHD ASMR attributed to APMP was 16.60 [95% Uncertainty Interval (UI), 13.61 to 19.44] per 100,000 population, with the highest APMP burden in middle SDI regions. From 1990 to 2019, the global ASMR for HAP-attributable IHD declined. The global ASMR of IHD attributable to HAP in 2019 was 6.30 (95% UI, 4.28 to 8.80) per 100,000 population, with the highest burden observed in the low SDI regions. From 1990 to 2019, the global burden of ASMR and ASDR of IHD attributable to APMP showed stabilization, whereas the HAP burden exhibited a decrease. There are a large burden of APMP particularly in middle SDI countries and a higher burden of HAP in low SDI countries. The burden of IHD due to APMP and HAP in men, the elderly, and populations in low, medium, and low SDI regions should be noticed.
缺血性心脏病（IHD）风险升高与接触细颗粒物有关。然而，关于因固体燃料造成的家庭空气污染（HAP）和环境颗粒物污染（APMP）导致的IHD全球负担的趋势和比较数据有限，尤其是在社会经济水平不同的地区。基于《2019年全球疾病负担研究》（GBD 2019），我们获取了1990年至2019年因APMP和HAP导致的IHD的年龄标准化死亡率（ASMR）和年龄标准化残疾调整生命年（ASDR）。通过Joinpoint模型计算了1990年至2019年期间归因于APMP和HAP的IHD负担趋势。我们使用局部加权回归模型估计了ASMR与社会人口学指数（SDI）以及医疗保健可及性和质量（HAQ）指数之间的关系。2019年，归因于APMP的IHD全球负担ASMR趋于稳定，但在中低SDI地区观察到了最显著的增加。归因于APMP的IHD全球ASMR为每10万人16.60 [95%不确定区间（UI），13.61至19.44]，中SDI地区的APMP负担最高。从1990年到2019年，归因于HAP的IHD全球ASMR下降。2019年归因于HAP的IHD全球ASMR为每10万人6.30（95% UI，4.28至8.80），低SDI地区的负担最高。从1990年到2019年，归因于APMP的IHD的全球ASMR和ASDR负担趋于稳定，而HAP负担则呈现下降趋势。APMP负担尤其在中SDI国家较重，而HAP负担在低SDI国家较高。应关注男性、老年人以及低、中、低SDI地区人群中因APMP和HAP导致的IHD负担。
