Kerwin Leonard Y, El Tal Abdel Kader, Stiff Mark A, Fakhouri Tarek M
Department of Dermatology, Wayne State University, Dearborn, MI, USA.
Int J Dermatol. 2014 Aug;53(8):922-36. doi: 10.1111/ijd.12436. Epub 2014 Apr 2.
Cosmetic, functional, and structural sequelae of scarring are innumerable, and measures exist to optimize and ultimately minimize these sequelae. To evaluate the innumerable methods available to decrease the cosmetic, functional, and structural repercussions of scarring, pubMed search of the English literature with key words scar, scar revision, scar prevention, scar treatment, scar remodeling, cicatrix, cicatrix treatment, and cicatrix remodeling was done. Original articles and reviews were examined and included. Seventy-nine manuscripts were reviewed. Techniques, comparisons, and results were reviewed and tabulated. Overall, though topical modalities are easier to use and are usually more attractive to the patient, the surgical approaches still prove to be superior and more reliable. However, advances in topical medications for scar modification are on the rise and a change towards medical treatment of scars may emerge as the next best approach. Comparison studies of the innumerable specific modalities for scar revision and prevention are impossible. Standardization of techniques is lacking. Scarring, the body's natural response to a wound, can create many adverse effects. At this point, the practice of sound, surgical fundamentals still trump the most advanced preventative methods and revision techniques. Advances in medical approaches are available, however, to assist the scarring process, which even the most advanced surgical fundamentals will ultimately lead to. Whether through newer topical therapies, light treatment, or classical surgical intervention, our treatment armamentarium of scars has expanded and will allow us to maximize scar prevention and to minimize scar morbidity.
瘢痕形成的美容、功能和结构后遗症数不胜数,现有多种措施可优化并最终减少这些后遗症。为评估减少瘢痕形成的美容、功能和结构影响的众多可用方法,我们在PubMed上检索了英文文献,关键词为瘢痕、瘢痕修复、瘢痕预防、瘢痕治疗、瘢痕重塑、瘢痕疙瘩、瘢痕疙瘩治疗和瘢痕疙瘩重塑。对原始文章和综述进行了审查并纳入。共审查了79篇手稿。对技术、比较和结果进行了审查并制成表格。总体而言,尽管局部治疗方法使用更简便,通常对患者更具吸引力,但手术方法仍被证明更优越、更可靠。然而,用于瘢痕改善的局部药物进展不断,向瘢痕药物治疗的转变可能成为下一个最佳方法。对无数瘢痕修复和预防的具体方法进行比较研究是不可能的。缺乏技术标准化。瘢痕形成是身体对伤口的自然反应,会产生许多不良影响。此时,扎实的手术基本功仍胜过最先进的预防方法和修复技术。不过,医学方法的进展可辅助瘢痕形成过程,即使是最先进的手术基本功最终也会导致瘢痕形成。无论是通过更新的局部治疗、光疗还是经典的手术干预,我们治疗瘢痕的手段已经扩大,将使我们能够最大限度地预防瘢痕并减少瘢痕的发病率。