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Takotsubo 综合征的临床特征:一系列病例。

Clinical characteristics of takotsubo syndrome: a series of cases.

机构信息

Servicio de Cardiología, Hospital de Especialidades No. 2, IMSS.

Departamento de Ciencias de la Salud, Universidad de Sonora. Ciudad Obregón, Son., México.

出版信息

Arch Cardiol Mex. 2023;93(2):203-211. doi: 10.24875/ACM.21000407.

DOI:10.24875/ACM.21000407
PMID:37037221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10161822/
Abstract

INTRODUCTION

takotsubo syndrome (TTS) is a recently recognized entity that resembles an acute coronary syndrome. Its epidemiology has been studied in various populations around the world. The most frequent trigger is an emotional stressful event.

OBJECTIVE

To describe the clinical characteristics of a series of cases with TTS.

MATERIAL AND METHODS

A descriptive and retrospective study was carried out. The variables of age, gender, clinical characteristics, cardiovascular risk factors, triggering factors, biomarkers, electrocardiographic, echocardiographic, and angiographic findings in the clinical records of a group of cases of patients with TTS were evaluated.

RESULTS

19 cases of TTS were included. There were 16 women and 3 men, the average age was 62 ± 14 years; the main cardiovascular risk factor was sedentary lifestyle in 13 cases. The emotional trigger was present in most cases. The most frequent symptom was chest pain, eight cases presented data of shoCKP and heart failure. The most common variant by echocardiography was apical ballooning in 79%, as well as by ventriculography. The most common complication was cardiogenic shoCKP.

CONCLUSIONS

The clinical characteristics of our population are like those previously described in the literature. TTS is a transient and reversible cardiomyopathy with a good prognosis.

摘要

简介

应激性心肌病(TTS)是一种新近被认识到的疾病实体,类似于急性冠状动脉综合征。其流行病学已在世界各地的不同人群中进行了研究。最常见的诱因是情绪应激事件。

目的

描述一系列 TTS 病例的临床特征。

材料和方法

进行了一项描述性和回顾性研究。评估了一组 TTS 患者的临床记录中的年龄、性别、临床特征、心血管危险因素、触发因素、生物标志物、心电图、超声心动图和血管造影发现等变量。

结果

共纳入 19 例 TTS 患者,其中 16 例为女性,3 例为男性,平均年龄为 62 ± 14 岁;主要心血管危险因素为 13 例患者的久坐生活方式。情绪诱因在大多数情况下存在。最常见的症状是胸痛,8 例出现 shoCKP 和心力衰竭的数据。超声心动图最常见的表现为心尖球囊样变,占 79%,心室造影也如此。最常见的并发症是心源性 shoCKP。

结论

我们人群的临床特征与文献中先前描述的相似。TTS 是一种短暂且可逆转的心肌病,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c17/10161822/2b617ac23750/7567AX222-ACM-93-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c17/10161822/2b617ac23750/7567AX222-ACM-93-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c17/10161822/2b617ac23750/7567AX222-ACM-93-203-g001.jpg

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本文引用的文献

1
Takotsubo cardiomyopathy misdiagnosed as acute myocardial infarction under the Chest Pain Center model: A case report.在胸痛中心模式下被误诊为急性心肌梗死的应激性心肌病:一例报告。
World J Clin Cases. 2022 Mar 16;10(8):2616-2621. doi: 10.12998/wjcc.v10.i8.2616.
2
Analysis of 9 Cases of Takotsubo Syndrome and an Analysis of the Clinical Characteristics of Takotsubo Syndrome From a Chinese Population.9例Takotsubo综合征分析及中国人群Takotsubo综合征临床特征分析
Front Cardiovasc Med. 2021 Oct 26;8:732193. doi: 10.3389/fcvm.2021.732193. eCollection 2021.
3
Long COVID Syndrome and Takotsubo Cardiomyopathy: An Unwelcome Combination.
长新冠综合征与应激性心肌病:一种不良组合
Cureus. 2021 Aug 31;13(8):e17590. doi: 10.7759/cureus.17590. eCollection 2021 Aug.
4
Takotsubo Cardiomyopathy: Current Treatment.应激性心肌病:当前的治疗方法
J Clin Med. 2021 Aug 2;10(15):3440. doi: 10.3390/jcm10153440.
5
A 'shark'-masked electrocardiogram: case report of a Tako-Tsubo syndrome.一例“鲨鱼”面具样心电图:应激性心肌病病例报告
Eur Heart J Case Rep. 2021 May 7;5(5):ytab132. doi: 10.1093/ehjcr/ytab132. eCollection 2021 May.
6
A case report of takotsubo syndrome complicated by ischaemic stroke: the clinical dilemma of anticoagulation.一例应激性心肌病合并缺血性卒中的病例报告:抗凝治疗的临床困境
Eur Heart J Case Rep. 2021 Mar 15;5(3):ytab051. doi: 10.1093/ehjcr/ytab051. eCollection 2021 Mar.
7
Takotsubo syndrome in association with pheochromocytoma: clinical and practical considerations.与嗜铬细胞瘤相关的 Takotsubo 综合征:临床和实际考虑。
Monaldi Arch Chest Dis. 2021 May 26;91(4). doi: 10.4081/monaldi.2021.1848.
8
Current Knowledge and Future Challenges in Takotsubo Syndrome: Part 1-Pathophysiology and Diagnosis.应激性心肌病的当前认知与未来挑战:第1部分——病理生理学与诊断
J Clin Med. 2021 Jan 28;10(3):479. doi: 10.3390/jcm10030479.
9
Takotsubo cardiomyopathy associated with bronchoscopic operation: A case report.与支气管镜手术相关的应激性心肌病:一例报告。
World J Clin Cases. 2020 Dec 26;8(24):6517-6523. doi: 10.12998/wjcc.v8.i24.6517.
10
Image Diagnosis: Takotsubo Cardiomyopathy Mimicking an Acute ST Elevation Myocardial Infarction in the Setting of Anti-Depressant Therapy Withdrawal.影像诊断:抗抑郁药停药后出现酷似急性 ST 段抬高型心肌梗死的 Takotsubo 心肌病。
Perm J. 2020;24. doi: 10.7812/TPP/19.095. Epub 2020 Apr 3.