Prea Selwyn, Guymer Robyn, Kong George, Vingrys Algis
Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne 3010, Australia.
Royal Victorian Eye and Ear Hospital, East Melbourne 3002, Australia.
J Clin Med. 2023 Mar 27;12(7):2530. doi: 10.3390/jcm12072530.
To determine the 12-month compliance with and retention of home monitoring (HM) with Melbourne Rapid Fields (MRFh) for patients with intermediate age-related macular degeneration (iAMD) and compare visual acuity (VA) and retinal sensitivity (RS) results to clinical measures.
Participants were recruited to a 12-month HM study with weekly testing of vision with MRFh. Inclusion criteria were a diagnosis of iAMD, understand English instructions, VA ≥ 20/40, and access to an iPad. Supervised in-clinic testing of high contrast VA (HVA, ETDRS), low-luminance VA (LLVA, ETDRS with ND2 filter), and RS (Macular Integrity Assessment, MAIA, and MRF in-clinic, MRFc) was conducted every 6-months.
A total of 54 participants (67 ± 6.8 years) were enrolled. Compliance to weekly HM was 61% and study retention at 12-months was 50% of those with uptake ( = 46). No difference was observed between MRFc and MRFh across all RS and VA outcomes ( > 0.05). MRFh RS was higher than MAIA (29.1 vs. 27.1 dB, < 0.001). MRFh HVA was not different from ETDRS ( = 0.08), but LLVA was 9 letters better (81.5 vs. 72.4 letters, < 0.001).
Over 12-months, MRFh yields a moderate level of compliance with (61%) and retention (50%) of weekly testing. Further studies are required to assess the ability of MRFh to detect early progression to nAMD.
确定中度年龄相关性黄斑变性（iAMD）患者使用墨尔本快速视野（MRFh）进行家庭监测（HM）的12个月依从性和保留率，并将视力（VA）和视网膜敏感度（RS）结果与临床测量结果进行比较。
招募参与者进行为期12个月的HM研究，每周使用MRFh测试视力。纳入标准为iAMD诊断、理解英语说明、VA≥20/40以及能够使用iPad。每6个月进行一次高对比度VA（HVA，ETDRS）、低亮度VA（LLVA，带ND2滤镜的ETDRS）和RS（黄斑完整性评估，MAIA，以及临床内MRF，MRFc）的监督性临床测试。
共招募了54名参与者（67±6.8岁）。每周HM的依从率为61%，12个月时的研究保留率为参与接受监测者的50%（n = 46）。在所有RS和VA结果中，MRFc和MRFh之间未观察到差异（P>0.05）。MRFh RS高于MAIA（29.1对27.1 dB，P<0.001）。MRFh HVA与ETDRS无差异（P = 0.08），但LLVA高9个字母（81.5对72.
