Junior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Str. 29, 07743 Jena, Germany.
Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Dornburger Str. 25, 07743 Jena, Germany.
Nutrients. 2023 Mar 28;15(7):1645. doi: 10.3390/nu15071645.
A 14-day randomized controlled study with a parallel design was conducted with 80 healthy participants. Intervention groups I (IG1) and II (IG2) received a defined background diet and consumed a smoothie enriched with either 15 g of dry weight (d.w.) or 15 g of d.w. daily. Control group II (CG2) received a defined background diet without the smoothie. Control group I (CG1) received neither. Blood samples and 24-h urine were collected at the beginning and the end of the study. Serum concentrations of 25-hydroxyvitamin D, vitamin D, selenium, iron, ferritin, transferrin saturation, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, non-HDL cholesterol and the LDL-cholesterol/HDL cholesterol ratio decreased in IG1 ( < 0.05), while 25-hydroxyvitamin D increased ( < 0.05). In IG2, vitamin D, 25-hydroxyvitamins D and D decreased ( < 0.05), while concentrations of fatty acids C20:5 and C22:5 increased. Serum and urine uric acid increased in IG1 and IG2 ( < 0.05). is a valuable source of n3 fatty acids, as is of vitamin D. Regular consumption of may affect the iron and selenium status negatively but may impact blood lipids positively. An elevated uric acid concentration in blood and urine following the regular consumption of microalgae poses potential risks for human health.
一项为期 14 天的随机对照平行设计研究纳入了 80 名健康参与者。干预组 I（IG1）和 II（IG2）接受了特定的基础饮食，并摄入富含 15 克干重（d.w.）或 15 克 d.w.的奶昔。对照组 II（CG2）接受了特定的基础饮食，但没有摄入奶昔。对照组 I（CG1）既没有摄入奶昔也没有接受基础饮食。在研究开始和结束时采集血清样本和 24 小时尿液。IG1 组（ < 0.05）血清 25-羟维生素 D、维生素 D、硒、铁、铁蛋白、转铁蛋白饱和度、总胆固醇、低密度脂蛋白（LDL）胆固醇、高密度脂蛋白（HDL）胆固醇、非高密度脂蛋白胆固醇和 LDL 胆固醇/HDL 胆固醇比值下降，而 25-羟维生素 D 增加（ < 0.05）。IG2 组维生素 D、25-羟维生素 D 和 D 下降（ < 0.05），而脂肪酸 C20:5 和 C22:5 浓度增加。IG1 和 IG2 组血清和尿液尿酸增加（ < 0.05）。小球藻是 n3 脂肪酸的宝贵来源，同样也是维生素 D 的来源。定期摄入小球藻可能会对铁和硒的状态产生负面影响，但可能会对血脂产生积极影响。尿酸在血液和尿液中的浓度升高，可能会对人类健康造成潜在风险。
