Kabakci Ayse Gul, Bozkır Dursun Murat, Cengizler Çağlar, Sire Eren Dilek, Bozkır Memduha Gülhal
Department of Anatomy, Faculty of Medicine, Cukurova University, Adana, Turkey.
Adana Sevgi Eye Center, Adana, Turkey.
Clin Cosmet Investig Dermatol. 2023 Apr 6;16:973-980. doi: 10.2147/CCID.S406173. eCollection 2023.
We performed an assessment of the rejuvenation effect of an amino acid and hyaluronic acid mixture in the periorbital area.
A total of 23 of the 35 participants completed all application sessions and measurements. These 23 women were aged 30-55 years. A hyaluronic acid and amino acid mixture was injected into the participants' periorbital area. Three sessions of application with 15-day intervals were undertaken. Subjects' age, height, weight, smoking status, and sport participation were recorded. A photonumeric dark circle scale and Fitzpatrick's periorbital wrinkling classification were used for evaluation of dark circles and wrinkles in the periorbital area. Anatomical measurements (height of upper and lower eyelids) were done using ImageJ and a skin-analysis system (Observ 520).
The 23 women had a mean age of 42.46±9.33 years, mean height 164.46±4.96 cm, and mean weight 63.94±8.26 kg. Before the sessions, the mean heights of the upper eyelids were 1.24±013 cm (right) and 1.21±013 cm (left), while those of the lower eyelids were 0.98±014 cm (right) and 0.97±0.17 cm (left). One month after the third session, mean upper-eyelid heights were 1.30±0.09 cm (right) and 1.28±0.11 cm (left) and lower-eyelid ones 1.02±0.11 cm (right) and 1.02±0.13 cm (left). Dark-circle and wrinkle-scale scores showed significantly positive results between before the sessions and 1 month after the third session.
A hyaluronic acid and amino acid mixture can be used to rejuvenation of the periorbital area in women aged 30-55 years.
我们对氨基酸和透明质酸混合物在眶周区域的年轻化效果进行了评估。
35名参与者中有23名完成了所有的涂抹疗程和测量。这23名女性年龄在30至55岁之间。将透明质酸和氨基酸混合物注射到参与者的眶周区域。进行了3个疗程，间隔15天。记录受试者的年龄、身高、体重、吸烟状况和运动参与情况。使用数字光子黑眼圈量表和菲茨帕特里克眶周皱纹分类法来评估眶周区域的黑眼圈和皱纹。使用ImageJ和皮肤分析系统（Observ 520）进行解剖学测量（上下眼睑的高度）。
这23名女性的平均年龄为42.46±9.33岁，平均身高164.46±4.96厘米，平均体重63.94±8.26千克。在疗程开始前，上眼睑的平均高度分别为右侧1.24±0.13厘米和左侧1.21±0.13厘米，而下眼睑的平均高度分别为右侧0.98±0.14厘米和左侧0.97±0.17厘米。在第三个疗程后1个月，上眼睑平均高度分别为右侧1.30±0.09厘米和左侧1.28±0.11厘米，下眼睑平均高度分别为右侧1.02±0.11厘米和左侧1.02±0.13厘米。黑眼圈和皱纹量表评分在疗程开始前和第三个疗程后1个月之间显示出显著的积极结果。
透明质酸和氨基酸混合物可用于30至55岁女性眶周区域的年轻化。
