Brisigotti M, Lorenzini P, Alessi A, Fabbretti G, Baldoni C
Tumori. 1986 Apr 30;72(2):211-4. doi: 10.1177/030089168607200217.
The authors studied a case of mucin-producing adenoma of the thyroid gland. The tumor consisted almost entirely of signet-ring cells containing mucin, which was strongly positive with PAS, with and without diastase pre-treatment, and Alcian blue stain at pH 2.5. Immunoperoxidase staining for thyreoglobulin was clearly positive within the cytoplasm of signet-ring cells and also in the follicle material, which indicates that the tumor derived from follicular epithelium.
作者研究了一例甲状腺黏液产生性腺瘤。肿瘤几乎完全由含有黏液的印戒细胞组成，该黏液经PAS染色（无论有无淀粉酶预处理）以及pH 2.5的阿尔辛蓝染色均呈强阳性。甲状腺球蛋白免疫过氧化物酶染色在印戒细胞的细胞质内以及滤泡物质中均呈明显阳性，这表明肿瘤起源于滤泡上皮。
