Luz Antonia, Rupp Rüdiger, Ahmadi Rezvan, Weidner Norbert
Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, 69118, Heidelberg, Germany.
Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Neurol Res Pract. 2023 Apr 13;5(1):14. doi: 10.1186/s42466-023-00241-z.
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative interventions can partially restore motor function and neurological recovery after spinal cord injury (SCI). In addition to the ESCS applications for improvement of upper and lower extremity function, ESCS has been investigated for treatment of autonomic dysfunction after SCI such as orthostatic hypotension. The aim of this overview is to present the background of ESCS, emerging concepts and its readiness to become a routine therapy in SCI beyond treatment of chronic pain conditions.
硬膜外脊髓电刺激（ESCS）是多种慢性疼痛病症中已确立的治疗选择。在过去十年中，概念验证研究表明，ESCS与以任务为导向的康复干预相结合，可部分恢复脊髓损伤（SCI）后的运动功能和神经恢复。除了将ESCS应用于改善上肢和下肢功能外，还对ESCS用于治疗SCI后的自主神经功能障碍（如体位性低血压）进行了研究。本综述的目的是介绍ESCS的背景、新出现的概念及其在SCI中成为常规治疗方法（而非仅用于治疗慢性疼痛病症）的可行性。
