Department of Ecological Physiology, Federal State Budgetary Scientific Institution "Institute of Experimental Medicine", 12 Academic Pavlov St, Saint-Petersburg, 197022, Russia.
J Physiol Anthropol. 2023 Apr 13;42(1):5. doi: 10.1186/s40101-023-00323-6.
This review focuses on the effects of different body positions on intracranial fluid dynamics, including cerebral arterial and venous flow, cerebrospinal fluid (CSF) hydrodynamics, and intracranial pressure (ICP). It also discusses research methods used to quantify these effects. Specifically, the implications of three types of body positions (orthostatic, supine, and antiorthostatic) on cerebral blood flow, venous outflow, and CSF circulation are explored, with a particular emphasis on cerebrovascular autoregulation during microgravity and head-down tilt (HDT), as well as posture-dependent changes in cerebral venous and CSF flow, ICP, and intracranial compliance (ICC). The review aims to provide a comprehensive analysis of intracranial fluid dynamics during different body positions, with the potential to enhance our understanding of intracranial and craniospinal physiology.
这篇综述重点关注了不同体位对颅内流体动力学的影响，包括脑动脉和静脉血流、脑脊液（CSF）动力学和颅内压（ICP）。还讨论了用于量化这些影响的研究方法。具体来说，探讨了三种体位（直立位、仰卧位和反直立位）对脑血流、静脉流出和 CSF 循环的影响，特别强调了微重力和头低位倾斜（HDT）期间的脑血管自动调节，以及与体位相关的脑静脉和 CSF 流量、ICP 和颅内顺应性（ICC）的变化。该综述旨在对不同体位时的颅内流体动力学进行全面分析，有潜力增进我们对颅内和颅脊生理学的理解。
