Bonnekoh B, Kuhn A
Z Hautkr. 1986 Mar 15;61(6):394-402.
Spinocellular carcinoma developed in a 19-year-old lesion of lichen ruber hypertrophicus of the lower leg. In the literature,24 cases of spinocellular carcinoma in lesions of cutaneous lichen ruber have been reported. X-ray and arsenic treatment has often preceded malignant transformation. Another risk factor seems to be the chronic hypertrophic type of lichen ruber located on the lower extremities.
在一例19年病程的小腿肥厚性红皮病皮损中发生了棘细胞癌。文献报道了24例皮肤红皮病皮损中发生棘细胞癌的病例。恶性转化前常先有X线和砷剂治疗史。另一个危险因素似乎是位于下肢的慢性肥厚型红皮病。