采用姐妹染色单体互换技术研究苯、甲苯和二甲苯的致突变作用。
The mutagenic effect of benzene, toluene and xylene studied by the SCE technique.
作者信息
Gerner-Smidt P, Friedrich U
出版信息
Mutat Res. 1978 Nov;58(2-3):313-6. doi: 10.1016/0165-1218(78)90024-1.
PMID:370577
Abstract
In experiments in vitro, neither benzene, toluene nor xylene changed the number of sister-chromatid exchanges (SCEs) or the number of chromosomal aberrations in human lymphocytes. Toluene and xylene caused a significant cell growth inhibition which was not observed with benzene in the same concentrations.
摘要
在体外实验中，苯、甲苯和二甲苯均未改变人淋巴细胞中的姐妹染色单体交换（SCE）数量或染色体畸变数量。甲苯和二甲苯引起显著的细胞生长抑制，而相同浓度的苯未观察到这种情况。
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