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乳乳铁蛋白是一种在人和动物体内具有铁结合能力的蛋白质,具有营养保健品和促进健康的潜力:当前的知识。

Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge.

机构信息

Fatima Memorial Hospital, College of Medicine and Dentistry, Shadman, Lahore, Pakistan.

Iqraa Medical Complex, Johar Town Lahore, Punjab, Pakistan.

出版信息

Biol Trace Elem Res. 2024 Jan;202(1):56-72. doi: 10.1007/s12011-023-03658-4. Epub 2023 Apr 14.

Abstract

Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile. Lactoferrin has been investigated for its numerous powerful influences, including anticancer, anti-inflammatory, anti-oxidant, anti-osteoporotic, antifungal, antibacterial, antiviral, immunomodulatory, hepatoprotective, and other beneficial health effects. Lactoferrin demonstrated several nutraceutical and pharmaceutical potentials and have a significant impact on improving the health of humans and animals. Lactoferrin plays a critical role in keeping the normal physiological homeostasis associated with the development of pathological disorders. The current review highlights the medicinal value, nutraceutical role, therapeutic application, and outstanding favorable health sides of lactoferrin, which would benefit from more exploration of this glycoprotein for the design of effective medicines, drugs, and pharmaceuticals for safeguarding different health issues in animals and humans.

摘要

乳铁蛋白是转铁蛋白家族中的一种天然阳离子铁结合糖蛋白,存在于牛乳和其他外分泌液中,包括泪液、唾液和胆汁。乳铁蛋白因其众多强大的影响而受到研究,包括抗癌、抗炎、抗氧化、抗骨质疏松、抗真菌、抗菌、抗病毒、免疫调节、保肝和其他有益的健康影响。乳铁蛋白表现出多种营养和药物潜力,对改善人类和动物的健康有重大影响。乳铁蛋白在保持与病理紊乱发展相关的正常生理动态平衡方面发挥着关键作用。本综述强调了乳铁蛋白的药用价值、营养作用、治疗应用和突出的健康益处,这将得益于对这种糖蛋白的进一步探索,以设计用于保护动物和人类不同健康问题的有效药物、药品和制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6421/10104436/065345ac84e3/12011_2023_3658_Fig1_HTML.jpg

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