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中低收入国家结直肠癌管理面临的挑战。

Challenges in the management of colorectal cancer in low- and middle-income countries.

机构信息

Department of Clinical Oncology, Bannu Institute of Nuclear Medicine Oncology and Radiotherapy (BINOR), Bannu, Khyber Pakhtunkhwa, Pakistan.

Head and Neck Surgery, National Institute of Oncology Hungary, Budapest, Hungary.

出版信息

Cancer Treat Res Commun. 2023;35:100705. doi: 10.1016/j.ctarc.2023.100705. Epub 2023 Apr 6.

DOI:10.1016/j.ctarc.2023.100705
PMID:37060879
Abstract

AIM

This narrative review aims to describe colorectal cancer (CRC) management landscape in low- and middle-income countries (LMICs), presenting the most recent and relevant papers on the topic. As a secondary aim, the authors suggest new ways of improving CRC patient care in LMICs.

BACKGROUND

Several studies show that the incidence of colon cancer in low- and middle-income countries (LMICs) is rising. In addition to the increasing incidence, lack of early detection and impeded access to optimal multidisciplinary treatment may worsen survival outcomes.

CONCLUSION

Developing quality diagnostic services in the proper health context is crucial for early diagnosis and successful therapy of CRC patients, and applying a resource-sensitive approach to prioritize essential treatments based on effectiveness and cost-effectiveness is key to overcoming barriers in LMICs, with clinical research collaborations between high-income countries (HICs) and LMICs being a helpful strategy to improve health indicators and prevent the burnout of health workers.

摘要

目的

本叙述性综述旨在描述中低收入国家(LMICs)的结直肠癌(CRC)管理现状,呈现该主题的最新和相关文献。作为次要目标,作者提出了改善 LMICs 中 CRC 患者护理的新方法。

背景

多项研究表明,中低收入国家(LMICs)的结肠癌发病率正在上升。除了发病率上升之外,早期检测的缺乏和对最佳多学科治疗的阻碍可能会使生存结果恶化。

结论

在适当的卫生环境中发展优质诊断服务对于 CRC 患者的早期诊断和成功治疗至关重要,并且应用资源敏感的方法根据有效性和成本效益来优先考虑基本治疗是克服 LMICs 障碍的关键,高收入国家(HICs)与 LMICs 之间的临床研究合作是改善卫生指标和防止卫生工作者倦怠的有益策略。

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