McGowan J A, Greenberg A
Am J Nephrol. 1986;6(2):135-9. doi: 10.1159/000167068.
Because antemortem diagnosis is difficult, renal failure due to cholesterol atheroembolism has, until recently, been regarded as a uniformly irreversible and generally fatal disease. Of late, recovery of renal function in several patients in whom the diagnosis was made by organ or other invasive biopsy has been reported. Three cases of cholesterol atheroembolic renal failure in which the diagnosis was made by simple, noninvasive biopsy of the skin in areas showing livedo reticularis are described. Two of the patients, including 1 who required dialysis for 2 months, had an extended survival with recovery of renal function.
由于生前诊断困难,直到最近,胆固醇动脉粥样硬化栓塞所致肾衰竭一直被视为一种完全不可逆且通常致命的疾病。近来,有报道称数例经器官或其他侵入性活检确诊的患者肾功能得以恢复。本文描述了3例胆固醇动脉粥样硬化栓塞性肾衰竭,其诊断是通过对出现网状青斑区域的皮肤进行简单的非侵入性活检作出的。其中2例患者,包括1例需要透析2个月的患者,存活期延长且肾功能恢复。