Shimoga Sandhya V, Lu Yang Z
Department of Health Care Administration, California State University Long Beach, Long Beach, CA, USA.
Heliyon. 2023 Mar 30;9(4):e14981. doi: 10.1016/j.heliyon.2023.e14981. eCollection 2023 Apr.
To examine the association between electronic prescribing of controlled substances (EPCS) and controlled substance prescription patterns in U.S. emergency departments (ED).
We conducted cross-sectional analysis at both the ED level and visit level, using the 2016-2017 National Hospital Ambulatory Medical Care Surveys.
The sample included 24,296 visits to 316 EDs, 45% of which utilized EPCS. Pain-related visits were associated with significantly higher odds of prescriptions for any controlled substances (OR = 1.52; 95% CI: 1.32-1.75; p < 0.001) and Schedule II substances (OR = 2.13; 95% CI: 1.80-2.52; p < 0.001). Conditional on pain-related visits, EPCS was significantly associated with higher odds of any (OR 1.31; 95% CI: 1.08-1.59; p = 0.006) and Schedule III (OR 1.38; 95% CI: 1.03-1.85; p = 0.031) controlled substance prescriptions. For non-pain related visits, EPCS was not associated with changes in controlled substance prescriptions.
While EPCS transmits prescriptions directly to pharmacies in order to reduce drug diversion problems, the results indicated no significant association between EPCS use and prescriptions for Schedule II drugs which include opioids. As many states move towards mandating EPCS use in order to curb the opioid epidemic, future studies should examine the barriers to the effective implementation of EPCS, in the context of other systems such as Prescription Drug Monitoring Programs.
EPCS does not appear to deter Schedule II controlled substances prescription including opioids in an ED visit. It may facilitate any and Schedule III controlled substance prescriptions when pain was involved in an ED visit.
研究美国急诊科(ED)中受控物质电子处方(EPCS)与受控物质处方模式之间的关联。
我们使用2016 - 2017年国家医院门诊医疗调查,在急诊科层面和就诊层面进行了横断面分析。
样本包括对316家急诊科的24296次就诊,其中45%使用了EPCS。与疼痛相关的就诊开具任何受控物质处方的几率显著更高(比值比[OR]=1.52;95%置信区间[CI]:1.32 - 1.75;p<0.001)以及开具附表II物质处方的几率显著更高(OR = 2.13;95% CI:1.80 - 2.52;p<0.001)。在与疼痛相关的就诊条件下,EPCS与开具任何受控物质(OR 1.31;95% CI:1.08 - 1.59;p = 0.006)和附表III受控物质(OR 1.38;95% CI:1.03 - 1.85;p = 0.031)处方的几率显著相关。对于与疼痛无关的就诊,EPCS与受控物质处方的变化无关。
虽然EPCS将处方直接传输到药房以减少药物转移问题,但结果表明EPCS的使用与包括阿片类药物在内的附表II药物处方之间没有显著关联。随着许多州为遏制阿片类药物流行而倾向于强制使用EPCS,未来的研究应在诸如处方药监测计划等其他系统的背景下,研究有效实施EPCS的障碍。
EPCS似乎不会抑制急诊科就诊时包括阿片类药物在内的附表II受控物质处方。当急诊科就诊涉及疼痛时,它可能会促进开具任何受控物质和附表III受控物质处方。