适用于资源匮乏地区的基于CRISPR的检测方法。
CRISPR-based assays for low-resource settings.
作者信息
Huang Zhen, Lyon Christopher J, Hu Tony Y
机构信息
National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen, Guangdong China.
Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA USA.
出版信息
Nat Rev Bioeng. 2023;1(4):230-231. doi: 10.1038/s44222-023-00026-8. Epub 2023 Jan 25.
CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them.
基于CRISPR的检测方法可在资源有限的环境中用作超灵敏分子诊断方法，但即时检测应用必须满足其他要求。在此，我们讨论开发这些检测方法的主要障碍，并就如何克服这些障碍提供见解。
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