Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China.
School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Front Public Health. 2023 Mar 29;11:1122509. doi: 10.3389/fpubh.2023.1122509. eCollection 2023.
In recent years, the incidence of obesity in people aged 60 and over has increased significantly, and abdominal obesity has been recognized as an independent risk factor for diabetes. Aging causes physiologic decline in multiple body systems, leading to changes in obesity indicators such as BMI. At present, the relationship between abdominal obesity markers and Diabetes mellitus (DM) in people aged 60 years and older remains unclear. Therefore, it is necessary to study the correlation between anthropometric indices and diabetes and explore potential predictors.
The basic demographic information of participants aged 60 and above in Zhongshan City in 2020 was collected. Physical parameters, blood glucose and other biochemical indices were measured comprehensively. Binary logistic regression analysis was used to explore the relationship between abdominal obesity indicators [Waist circumference, Neck Circumference, Waist-to-hip ratio, Chinese Visceral Obesity Index (CVAI), and visceral obesity index] and diabetes mellitus. ROC characteristic curve was used to analyze the predictive ability of abdominal obesity indicators to DM, and the non-restrictive cubic spline graph was used to visualize the screened obesity indicators and diabetes risk.
Among 9,519 participants, the prevalence of diabetes was 15.5%. Compared with low CVAI, High CVAI level was significantly associated with increased prevalence of DM in males and females (all < 0.05), in males (OR, 2.226; 95%CI: 1.128-4.395), females (OR, 1.645; 95%CI: 1.013-2.669). After adjusting for potential confounding factors, there were gender differences between neck circumference and the prevalence of DM, and above-normal neck circumference in males was significantly associated with increased prevalence of DM (OR, 1.381; 95% CI: 1.091-1.747) ( < 0.05).
Among these anthropometric indices, CVAI is consistent with the features of fat distribution in older individuals and shows superior discriminative power as a potential predictor of DM, compared to traditional anthropometric parameters.
近年来，60 岁及以上人群肥胖的发病率显著增加，腹部肥胖已被认为是糖尿病的独立危险因素。衰老导致多个身体系统的生理功能下降，导致 BMI 等肥胖指标发生变化。目前，60 岁及以上人群腹部肥胖标志物与糖尿病之间的关系尚不清楚。因此，有必要研究人体测量指标与糖尿病之间的相关性，并探索潜在的预测指标。
收集 2020 年中山市 60 岁及以上人群的基本人口统计学信息。全面测量身体参数、血糖等生化指标。采用二元逻辑回归分析探讨腹部肥胖指标[腰围、颈围、腰臀比、中国内脏肥胖指数（CVAI）和内脏肥胖指数]与糖尿病之间的关系。ROC 特征曲线分析腹部肥胖指标对 DM 的预测能力，非限制性三次样条图可视化筛选出的肥胖指标与糖尿病风险。
在 9519 名参与者中，糖尿病的患病率为 15.5%。与低 CVAI 相比，高 CVAI 水平与男性和女性 DM 的患病率增加显著相关（均<0.05），男性（OR，2.226；95%CI：1.128-4.395），女性（OR，1.645；95%CI：1.013-2.669）。调整潜在混杂因素后，颈围与 DM 患病率之间存在性别差异，男性颈围高于正常值与 DM 患病率增加显著相关（OR，1.381；95%CI：1.091-1.747）（<0.05）。
在这些人体测量指标中，CVAI 与老年人脂肪分布的特征一致，作为 DM 的潜在预测指标，其判别能力优于传统的人体测量参数。
