Colosimo Manuela, Luciani Filippo, Pullano Maria Novella, Abrego-Guandique Diana Marisol, Gallelli Luca
Department of Microbiology and Virology, AO Dulbecco: Pugliese Hospital, 88100 Catanzaro, Italy.
Infectious Disease Ambulatory, Department of Prevention, ASP, 87100 Cosenza, Italy.
Reports (MDPI). 2024 Nov 2;7(4):90. doi: 10.3390/reports7040090.
is a Gram-negative opportunistic and emerging pathogen able to induce systemic manifestations (e.g., peritonitis, pneumonia, urinary tract infections, meningitis) in immunocompromised patients. No data on children have been published. A 2-year-old child presented in the pediatric ambulatory room with recurrent fever, submandibular lymphadenopathy, and skin rash. Laboratory findings revealed the presence of microcytic anemia with an increase in c-reactive protein. Chest X-ray reported mild accentuation of the bronchial structure, especially on the right side and middle-lower zone. In the peripheral blood smear, anisopoikilocytosis and elliptical red cells were evident. Clinical evaluation revealed the presence of conjunctivitis and polymorphic erythema, hyperemic pharynx and tonsils, SPO2 99%, auscultation of the chest, harsh vesicular murmur all over the area, and some wheezing. Microbiological analysis of sputum and throat swabs revealed the presence of numerous colonies of confirmed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS score > 2.2). This is the first case of post-COVID in a child. We suggest that a quick identification and an appropriate treatment represent the critical factors able to prevent the adverse outcomes related to infection.
是一种革兰氏阴性机会性和新兴病原体,能够在免疫功能低下的患者中诱发全身表现(如腹膜炎、肺炎、尿路感染、脑膜炎)。尚未发表关于儿童的相关数据。一名2岁儿童在儿科门诊就诊,有反复发热、颌下淋巴结肿大和皮疹。实验室检查发现存在小细胞性贫血,C反应蛋白升高。胸部X线报告显示支气管结构轻度增粗,尤其是右侧及中下区域。外周血涂片显示明显的红细胞大小不均和椭圆形红细胞。临床评估发现有结膜炎和多形性红斑、咽部和扁桃体充血、血氧饱和度99%、胸部听诊、全区域粗糙的水泡音以及一些哮鸣音。痰液和咽拭子的微生物学分析显示存在大量菌落,通过基质辅助激光解吸/电离飞行时间质谱法确认(MALDI-TOF MS评分>2.2)。这是儿童新冠后首例该病例。我们建议快速识别和适当治疗是能够预防与该感染相关不良后果至关重要的因素。