Secretaria de Estado da Saúde -SES/Superintendência de Vigilância em Saúde-SUVISA/GO, Gerência de Vigilância Epidemiológica-GVE, Rua 136 Qd F44 Lt 22/24 Ed Cesar Sebba - Setor Sul, Goiânia, Goiânia, Goiás, 74-093-250, Brazil.
Coordenação de Doenças Imunopreviníveis e Respiratórias, Goiânia, Brazil.
Arch Virol. 2023 Apr 17;168(5):142. doi: 10.1007/s00705-023-05748-z.
Here, we describe the clinical and laboratory characteristics of patients diagnosed with multisystem inflammatory syndrome in children (MIS-C) in the state of Goiás, Brazil, and its possible association with COVID-19. The study subjects were individuals aged between 0 and 19 years, selected from private and public institutions from May 2020 to April 2022. Thirty-five cases of MIS-C were confirmed. Four progressed to death. Most of the patients were 0-9 years old. All had fever, and 71.4% had abdominal pain. All had elevated levels of inflammatory markers, and 40.0% were positive for SARS-CoV-2 by RT-PCR. This study demonstrates a broad relationship between MIS-C and SARS-CoV-2 infection. Further studies are needed to confirm this association.
在这里，我们描述了巴西戈亚斯州诊断为儿童多系统炎症综合征 (MIS-C) 的患者的临床和实验室特征，以及其与 COVID-19 的可能关联。研究对象为 2020 年 5 月至 2022 年 4 月期间从私立和公立机构中选择的 0 至 19 岁的个体。共确诊 35 例 MIS-C。有 4 例进展为死亡。大多数患者为 0-9 岁。所有患者均有发热，71.4%有腹痛。所有患者的炎症标志物水平均升高，40.0%的患者通过 RT-PCR 检测 SARS-CoV-2 呈阳性。本研究表明 MIS-C 与 SARS-CoV-2 感染之间存在广泛的关系。需要进一步的研究来证实这种关联。
