Department of Anesthesiology, Xinqiao Hospital of Chongqing, Second Affiliated Hospital of Army Medical University, PLA, Chongqing, 400037, China.
J Cardiothorac Surg. 2023 Apr 17;18(1):147. doi: 10.1186/s13019-023-02223-3.
Acute aortic dissection (AAD) is a severe cardiovascular disease characterized by rapid progress and a high mortality rate. The incidence of acute aortic dissection is approximately 5 to 30 per 1 million people worldwide. In clinical practice, about 35% of AAD patients are complicated with acute lung injury (ALI). AAD complicated with ALI can seriously affect patients' prognosis and even increase mortality. However, the pathogenesis of AAD combined with ALI remains largely unknown. Given the public health burden of AAD combined with ALI, we reviewed the anesthetic management advances and highlighted potential areas for clinical practice.
急性主动脉夹层（AAD）是一种严重的心血管疾病，其特点是进展迅速，死亡率高。全球范围内，急性主动脉夹层的发病率约为每 100 万人中有 5 至 30 例。在临床实践中，约 35%的 AAD 患者并发急性肺损伤（ALI）。AAD 合并 ALI 可严重影响患者的预后，甚至增加死亡率。然而，AAD 合并 ALI 的发病机制在很大程度上尚不清楚。鉴于 AAD 合并 ALI 给公众健康带来的负担，我们回顾了麻醉管理方面的进展，并强调了潜在的临床实践领域。
