Department of Psychosomatic Medicine and Psychotherapy, LWL-University Hospital Bochum, Ruhr University Bochum, Bochum, Germany.
Department of Neuropsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr University Bochum, Bochum, Germany.
Eur J Psychotraumatol. 2023;14(2):2172258. doi: 10.1080/20008066.2023.2172258.
The Behavioural Inhibition System (BIS) as a neural system controlling motivation and behaviour, has previously been linked to multiple mental disorders, including Post-traumatic Stress Disorder (PTSD). BIS-sensitivity could increase the likelihood of PTSD development after trauma. However, previous studies have largely measured BIS-sensitivity retrospectively (i.e. after trauma, or even after onset of PTSD).
The study aims to confirm the relationship between BIS-sensitivity prior to trauma and PTSD symptoms.
After assessment of BIS-sensitivity, = 119 healthy participants watched a film with visually disturbing material. After 72 h, participants completed a questionnaire on PTSD-related symptoms (PCL-5).
In a multiple linear regression model, BIS-sensitivity significantly predicted PTSD symptoms, even after controlling for the decrease in mood, as well as for participants' age and sex, two factors that had previously been shown to influence BIS-sensitivity.
This is the first study to measure BIS-sensitivity before the occurrence of the (experimental) trauma and strengthens its role as a potential pre-traumatic risk factor.
行为抑制系统（BIS）作为一个控制动机和行为的神经系统，先前与多种精神障碍有关，包括创伤后应激障碍（PTSD）。BIS 敏感性可能会增加创伤后发生 PTSD 的可能性。然而，先前的研究主要是回顾性地测量 BIS 敏感性（即在创伤后，甚至在 PTSD 发作后）。
本研究旨在证实创伤前 BIS 敏感性与 PTSD 症状之间的关系。
在评估 BIS 敏感性后，=119 名健康参与者观看了一部带有视觉干扰材料的电影。72 小时后，参与者完成了一份关于 PTSD 相关症状的问卷（PCL-5）。
在多元线性回归模型中，BIS 敏感性显著预测 PTSD 症状，即使在控制情绪下降以及参与者年龄和性别（这两个先前被证明会影响 BIS 敏感性的因素）之后也是如此。
这是第一项在（实验）创伤发生之前测量 BIS 敏感性的研究，它加强了 BIS 敏感性作为潜在创伤前风险因素的作用。
