• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

青春期对血压轨迹的影响——潜在机制。

Effects of Puberty on Blood Pressure Trajectories - Underlying Processes.

机构信息

Department of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Pediatric Institute, Jagiellonian University Medical College, Kraków, Poland.

Department of Pediatric Nephrology and Hypertension, Chair of Pediatrics, Pediatric Institute, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Curr Hypertens Rep. 2023 Jul;25(7):117-125. doi: 10.1007/s11906-023-01241-9. Epub 2023 Apr 18.

DOI:10.1007/s11906-023-01241-9
PMID:37071287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10224830/
Abstract

Puberty is a complex process leading to physical, sexual, and psychosocial maturation. The changes in morphology and organ function during puberty also affect blood pressure (BP) regulation, and as a consequence (BP) values change noticeably, reaching values often higher than after reaching full maturity. In children entering puberty, BP, especially systolic, increases and then reaches adult values by the end of puberty. The mechanisms responsible for this process are complex and not fully understood. Sex hormones, growth hormone, insulin-like growth factor-1, and insulin, whose production increases during puberty, significantly regulate BP through complex and overlapping mechanisms. During puberty, the incidence of arterial hypertension also increases, especially in children with excess body weight. The present paper presents the current state of knowledge regarding the influence of processes occurring during puberty on blood pressure.

摘要

青春期是一个复杂的过程,导致身体、性和心理社会的成熟。青春期期间形态和器官功能的变化也会影响血压(BP)调节,因此(BP)值会发生明显变化,达到的值通常高于完全成熟后的值。在进入青春期的儿童中,血压,特别是收缩压,会升高,然后在青春期结束时达到成人值。负责这一过程的机制很复杂,尚未完全理解。在青春期,生产增加的性激素、生长激素、胰岛素样生长因子-1 和胰岛素通过复杂和重叠的机制显著调节血压。在青春期,动脉高血压的发病率也会增加,尤其是在超重的儿童中。本文介绍了青春期发生的过程对血压的影响的现有知识状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ea/10224830/fdcd1c7a7315/11906_2023_1241_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ea/10224830/d91972c77289/11906_2023_1241_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ea/10224830/fdcd1c7a7315/11906_2023_1241_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ea/10224830/d91972c77289/11906_2023_1241_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ea/10224830/fdcd1c7a7315/11906_2023_1241_Fig2_HTML.jpg

相似文献

1
Effects of Puberty on Blood Pressure Trajectories - Underlying Processes.青春期对血压轨迹的影响——潜在机制。
Curr Hypertens Rep. 2023 Jul;25(7):117-125. doi: 10.1007/s11906-023-01241-9. Epub 2023 Apr 18.
2
Sex steroids, growth hormone, insulin-like growth factor-1: neuroendocrine and metabolic regulation in puberty.性类固醇、生长激素、胰岛素样生长因子-1:青春期的神经内分泌与代谢调节
Horm Res. 1996;45(1-2):74-80. doi: 10.1159/000184763.
3
Predicting heart growth during puberty: The Muscatine Study.预测青春期心脏发育:马斯卡廷研究。
Pediatrics. 2000 May;105(5):E63. doi: 10.1542/peds.105.5.e63.
4
Relationship of body size and body mass to blood pressure: sex-specific and developmental influences.体型和体重与血压的关系:性别特异性及发育影响
Hum Biol. 1999 Aug;71(4):505-28.
5
The change in blood pressure during pubertal growth.青春期生长期间血压的变化。
J Clin Endocrinol Metab. 2005 Jan;90(1):163-7. doi: 10.1210/jc.2004-0926. Epub 2004 Oct 27.
6
Pubertal hypertension is a strong predictor for the risk of adult hypertension.青春期高血压是成年期高血压发病风险的一个强有力预测指标。
Biomed Environ Sci. 2011 Oct;24(5):459-66. doi: 10.3967/0895-3988.2011.05.002.
7
Gender differences in serum angiotensin-converting enzyme activity and blood pressure in children: an observational study.儿童血清血管紧张素转换酶活性和血压的性别差异:一项观察性研究。
Arq Bras Cardiol. 2008 Dec;91(6):352-7. doi: 10.1590/s0066-782x2008001800005.
8
Serum uric acid and blood pressure in children at cardiovascular risk.儿童心血管风险相关的血尿酸与血压
Pediatrics. 2013 Jul;132(1):e93-9. doi: 10.1542/peds.2013-0047. Epub 2013 Jun 17.
9
Sex-related influence of body size and sexual maturation on blood pressure in adolescents.青少年身体大小和性成熟对血压的性别相关影响。
Eur J Clin Nutr. 1999 Apr;53(4):333-7. doi: 10.1038/sj.ejcn.1600731.
10
Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children.体育锻炼可降低青春期前肥胖儿童的系统性血压,并改善动脉粥样硬化的早期标志物。
J Am Coll Cardiol. 2009 Dec 15;54(25):2396-406. doi: 10.1016/j.jacc.2009.08.030.

引用本文的文献

1
Aerobic fitness, lipid ratio, visceral adiposity index and risk of hypertension in adolescents: An observational study.青少年有氧适能、血脂比例、内脏脂肪肥胖指数与高血压风险:一项观察性研究。
World J Clin Pediatr. 2025 Sep 9;14(3):105939. doi: 10.5409/wjcp.v14.i3.105939.
2
Cross-sectional association of fitness, fatness, and dyslipidemia with metabolic syndrome in youth.青少年中体能、肥胖及血脂异常与代谢综合征的横断面关联
World J Clin Pediatr. 2025 Sep 9;14(3):107054. doi: 10.5409/wjcp.v14.i3.107054.
3
Prenatal Per- and Polyfluoroalkyl Substance Exposures and Longitudinal Blood Pressure Measurements in Children Aged 3 to 18 Years: Findings From a Racially and Ethnically Diverse US Birth Cohort.

本文引用的文献

1
Endothelial dysfunction as a factor leading to arterial hypertension.内皮功能障碍作为导致动脉高血压的一个因素。
Pediatr Nephrol. 2023 Sep;38(9):2973-2985. doi: 10.1007/s00467-022-05802-z. Epub 2022 Nov 21.
2
Central regulation of body fluid homeostasis.体液稳态的中枢调节。
Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(7):283-324. doi: 10.2183/pjab.98.016.
3
Association of Puberty Stage and Weight Status with Cardiometabolic Risk in Children and Adolescents Living on the Texas-Mexico Border.德克萨斯州-墨西哥边境地区儿童和青少年的青春期阶段和体重状况与心血管代谢风险的关联。
美国一个种族和民族多样化的出生队列中3至18岁儿童的产前全氟和多氟烷基物质暴露与纵向血压测量:研究结果
J Am Heart Assoc. 2025 Jun 17;14(12):e039949. doi: 10.1161/JAHA.124.039949. Epub 2025 Jun 12.
4
High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls.高强度间歇训练可降低超重/肥胖女孩的肝酶水平并改善与代谢功能障碍相关脂肪性肝病(MASLD)相关的生物标志物。
Nutrients. 2025 Jan 1;17(1):164. doi: 10.3390/nu17010164.
5
Relationship Between Dietary Patterns and Blood Pressure During Adolescence: A Longitudinal Analysis From Dados Study.青少年时期饮食模式与血压之间的关系:来自Dados研究的纵向分析
Am J Hum Biol. 2025 Jan;37(1):e24199. doi: 10.1002/ajhb.24199.
6
Lifelong impact of elevated blood pressure from childhood to adulthood.从童年到成年期血压升高的终身影响。
Clin Exp Pediatr. 2025 Apr;68(4):278-286. doi: 10.3345/cep.2024.01445. Epub 2024 Nov 28.
7
Metabolomic signatures for blood pressure from early to late adolescence: findings from a U.S. cohort.从青少年早期到晚期的血压代谢特征:来自美国队列的研究结果。
Metabolomics. 2024 May 9;20(3):52. doi: 10.1007/s11306-024-02110-5.
8
Association between Expression of Insulin-like Growth Factor-1 (IGF-1), IGF-1 Receptor (IGF-1R), and Hypertension-Mediated Organ Damage (HMOD) Parameters in Leukocytes and Plasma of Children/Adolescents with Primary Hypertension.原发性高血压儿童/青少年白细胞和血浆中胰岛素样生长因子-1(IGF-1)、IGF-1受体(IGF-1R)的表达与高血压介导的器官损伤(HMOD)参数之间的关联。
J Pers Med. 2024 Feb 28;14(3):255. doi: 10.3390/jpm14030255.
9
Psychosocial and environmental risk factors of obesity and hypertension in children and adolescents-a literature overview.儿童和青少年肥胖与高血压的社会心理和环境风险因素——文献综述
Front Cardiovasc Med. 2023 Nov 20;10:1268364. doi: 10.3389/fcvm.2023.1268364. eCollection 2023.
10
Impact of puberty, sex determinants and chronic inflammation on cardiovascular risk in young people.青春期、性别决定因素和慢性炎症对年轻人心血管风险的影响。
Front Cardiovasc Med. 2023 Jun 27;10:1191119. doi: 10.3389/fcvm.2023.1191119. eCollection 2023.
Metab Syndr Relat Disord. 2022 Oct;20(8):440-450. doi: 10.1089/met.2021.0151. Epub 2022 Jul 11.
4
Puberty Timing and Sex-Specific Trajectories of Systolic Blood Pressure: a Prospective Cohort Study.青春期启动时间与收缩压的性别特异性变化轨迹:一项前瞻性队列研究。
Hypertension. 2022 Aug;79(8):1755-1764. doi: 10.1161/HYPERTENSIONAHA.121.18531. Epub 2022 May 19.
5
Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile.成年人生长激素缺乏症及替代疗法对心血代谢风险特征的影响。
Pituitary. 2022 Apr;25(2):211-228. doi: 10.1007/s11102-022-01207-1. Epub 2022 Feb 1.
6
Obesity and Cardiometabolic Risk Factors: From Childhood to Adulthood.肥胖与心脏代谢危险因素:从儿童到成年。
Nutrients. 2021 Nov 22;13(11):4176. doi: 10.3390/nu13114176.
7
Linear growth and puberty in childhood obesity: what is new?儿童肥胖症的线性生长和青春期:有何新进展?
Minerva Pediatr (Torino). 2021 Dec;73(6):563-571. doi: 10.23736/S2724-5276.21.06543-5. Epub 2021 Jul 26.
8
Association between pubertal development and elevated blood pressure in children.青春期发育与儿童高血压的关系。
J Clin Hypertens (Greenwich). 2021 Aug;23(8):1498-1505. doi: 10.1111/jch.14315. Epub 2021 Jul 3.
9
Normal and Premature Adrenarche.正常和过早性肾上腺功能初现
Endocr Rev. 2021 Nov 16;42(6):783-814. doi: 10.1210/endrev/bnab009.
10
Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review.超生理剂量外源性雄激素对血小板活性及其血栓形成潜能的影响:文献综述
J Clin Med. 2021 Jan 4;10(1):147. doi: 10.3390/jcm10010147.