Rainwater L M, Martin J K, Gaffey T A, van Heerden J A
Arch Surg. 1986 Jun;121(6):669-72. doi: 10.1001/archsurg.1986.01400060063008.
The clinical histories, operative reports, and pathologic slides of 20 patients seen between 1907 and 1984 with diagnoses of angiosarcoma, hemangiosarcoma, and hemangioendothelioma were reviewed. The mean age of the 19 female patients and one male patient was 40.05 years (range, 16 to 67 years). Ten patients had the right breast involved, and five patients had contralateral breast involvement. Presenting symptoms included a mass in 20 patients, pain in ten patients, and breast discoloration in six patients. Before referral, ten patients had the misdiagnosis of a benign breast lesion. Because of the deceptively benign appearance of many angiosarcomas, these lethal tumors are often misdiagnosed as benign hemangiomas. Simple mastectomy is the treatment of choice, while adjuvant therapy remains to be evaluated.
回顾了1907年至1984年间诊断为血管肉瘤、血管内皮肉瘤和血管外皮细胞瘤的20例患者的临床病史、手术报告和病理切片。19例女性患者和1例男性患者的平均年龄为40.05岁（范围16至67岁）。10例患者右侧乳房受累，5例患者对侧乳房受累。主要症状包括20例患者有肿块，10例患者有疼痛，6例患者有乳房变色。转诊前，10例患者被误诊为良性乳腺病变。由于许多血管肉瘤外观具有欺骗性的良性特征，这些致命肿瘤常被误诊为良性血管瘤。单纯乳房切除术是首选治疗方法，而辅助治疗仍有待评估。
