Lober U, Geinitz D, Richter G, Flachowsky G, Hennig A
Arch Tierernahr. 1986 Jan;36(1):99-106. doi: 10.1080/17450398609425245.
In two feeding experiments fattening bulls received on average a daily supplement of 170 or 200 mg Monensin. In a further 8-week experiment the daily Monensin supplement was 0; 500 or 1 000 mg per day. Ergotropic Monensin supplements (experiments 1 and 2) did not change the blood count and the Ca, P and Mg content of blood serum and the activity of AP, AST and LAP in the serum remained unchanged. Net acid base excretion and the content of Na, K and Mg in urine were not significantly influenced either. The influence of 500 mg Monensin per animal and day on the feed intake of animals previously given lower supplements was insignificant. 1 000 mg Monensin per animal and day resulted in a 40% decrease of feed intake and permanent diarrhoea. It was connected with a diminishing of the glucose content in the blood and an increase of net acid base, Na and P excretion in urine. The blood count did not change after the Monensin overdose. In conclusion one can say that the ergotropic Monensin supplement did not change the metabolism parameters.
在两项饲养实验中,育肥牛平均每天补充170或200毫克莫能菌素。在另一项为期8周的实验中,每天莫能菌素的补充量为0;500或1000毫克。促肾上腺能莫能菌素补充剂(实验1和2)未改变血细胞计数以及血清中钙、磷和镁的含量,血清中碱性磷酸酶(AP)、天冬氨酸转氨酶(AST)和亮氨酸氨基肽酶(LAP)的活性也保持不变。净酸碱排泄以及尿液中钠、钾和镁的含量也未受到显著影响。每只动物每天500毫克莫能菌素对先前补充量较低的动物采食量的影响不显著。每只动物每天1000毫克莫能菌素导致采食量减少40%并出现持续性腹泻。这与血液中葡萄糖含量降低以及尿液中净酸碱、钠和磷排泄增加有关。莫能菌素过量后血细胞计数未发生变化。总之,可以说促肾上腺能莫能菌素补充剂未改变代谢参数。