A simple method to measure the gating latencies in photon and proton based radiotherapy using a scintillating crystal.

BACKGROUND

In respiratory gated radiotherapy, low latency between target motion into and out of the gating window and actual beam-on and beam-off is crucial for the treatment accuracy. However, there is presently a lack of guidelines and accurate methods for gating latency measurements.

PURPOSE

To develop a simple and reliable method for gating latency measurements that work across different radiotherapy platforms.

METHODS

Gating latencies were measured at a Varian ProBeam (protons, RPM gating system) and TrueBeam (photons, TrueBeam gating system) accelerator. A motion-stage performed 1 cm vertical sinusoidal motion of a marker block that was optically tracked by the gating system. An amplitude gating window was set to cover the posterior half of the motion (0-0.5 cm). Gated beams were delivered to a 5 mm cubic scintillating ZnSe:O crystal that emitted visible light when irradiated, thereby directly showing when the beam was on. During gated beam delivery, a video camera acquired images at 120 Hz of the moving marker block and light-emitting crystal. After treatment, the block position and crystal light intensity were determined in all video frames. Two methods were used to determine the gate-on (τ ) and gate-off (τ ) latencies. By method 1, the video was synchronized with gating log files by temporal alignment of the same block motion recorded in both the video and the log files. τ was defined as the time from the block entered the gating window (from gating log files) to the actual beam-on as detected by the crystal light. Similarly, τ was the time from the block exited the gating window to beam-off. By method 2, τ and τ were found from the videos alone using motion of different sine periods (1-10 s). In each video, a sinusoidal fit of the block motion provided the times T of the lowest block position. The mid-time, T , of each beam-on period was determined as the time halfway between crystal light signal start and end. It can be shown that the directly measurable quantity T - T  = (τ +τ )/2, which provided the sum (τ +τ ) of the two latencies. It can also be shown that the beam-on (i.e., crystal light) duration ΔT increases linearly with the sine period and depends on τ - τ : ΔT  = constant•period+(τ - τ ). Hence, a linear fit of ΔT as a function of the period provided the difference of the two latencies. From the sum (τ +τ ) and difference (τ - τ ), the individual latencies were determined.

RESULTS

Method 1 resulted in mean (±SD) latencies of τ  = 255 ± 33 ms, τ  = 82 ± 15 ms for the ProBeam and τ  = 84 ± 13 ms, τ  = 44 ± 11 ms for the TrueBeam. Method 2 resulted in latencies of τ  = 255 ± 23 ms, τ  = 95 ± 23 ms for the ProBeam and τ  = 83 ± 8 ms, τ  = 46 ± 8 ms for the TrueBeam. Hence, the mean latencies determined by the two methods agreed within 13 ms for the ProBeam and within 2 ms for the TrueBeam.

CONCLUSIONS

A novel, simple and low-cost method for gating latency measurements that work across different radiotherapy platforms was demonstrated. Only the TrueBeam fully fulfilled the AAPM TG-142 recommendation of maximum 100 ms latencies.