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[向大鼠背侧海马体注射血清素对条件性被动和主动回避反应的影响比较]

[Comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats].

作者信息

Gasanov G G, Melikov E M, Movsumov G D

出版信息

Biull Eksp Biol Med. 1986 May;101(5):517-9.

PMID:3708128
Abstract

It has been established that intrahippocampal bilateral injection of 5-HT in a dose of 2 micrograms prolonged the time of passive avoidance reflex retention, inhibiting the retrieval of active avoidance reflex and facilitating its extinction. The data obtained show the dependence of 5-HT effect on reinforcing and triggering properties of spatial-environmental and phasic conditioned stimuli. It is suggested that intrahippocampal 5-HT administration was responsible for the retrieval of traces of conditioned reinforced stimuli.

摘要

已经确定,以2微克的剂量双侧海马内注射5-羟色胺(5-HT)可延长被动回避反射保持的时间,抑制主动回避反射的恢复并促进其消退。所获得的数据表明5-HT效应依赖于空间环境和相位条件刺激的强化和触发特性。有人提出,海马内注射5-HT是导致条件强化刺激痕迹恢复的原因。

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[Comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats].[向大鼠背侧海马体注射血清素对条件性被动和主动回避反应的影响比较]
Biull Eksp Biol Med. 1986 May;101(5):517-9.
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[Effects of intrahippocampal injection of 6-OHDA on acquisition and retention of avoidance response in rats].[海马内注射6-羟基多巴胺对大鼠回避反应获得与保持的影响]
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[The pre- and postsynaptic mechanisms of the involvement of the serotonin of the amygdaloid body in the reproduction of the conditioned passive avoidance reaction in rats].
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Genomic and nongenomic effects of intrahippocampal microinjection of testosterone on long-term memory in male adult rats.海马体内微量注射睾酮对成年雄性大鼠长期记忆的基因组和非基因组效应
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Lesions of the ventral hippocampus, but not the dorsal hippocampus, impair conditioned fear expression and inhibitory avoidance on the elevated T-maze.腹侧海马体而非背侧海马体的损伤,会损害在高架T迷宫上的条件性恐惧表达和抑制性回避。
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[Effect of noradrenaline, microapplied to the dorsal hippocampus of the rat, on conditioned reflex memory].[微量注射去甲肾上腺素于大鼠背侧海马对条件反射记忆的影响]
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Stimulation of 5-HT(1A) receptors in the dorsal raphe ameliorates the impairment of spatial learning caused by intrahippocampal 7-chloro-kynurenic acid in naive and pretrained rats.刺激中缝背核中的5-羟色胺(5-HT)1A受体可改善幼稚和预训练大鼠海马内注射7-氯犬尿烯酸所导致的空间学习障碍。
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