Gasanov G G, Melikov E M, Movsumov G D
Biull Eksp Biol Med. 1986 May;101(5):517-9.
It has been established that intrahippocampal bilateral injection of 5-HT in a dose of 2 micrograms prolonged the time of passive avoidance reflex retention, inhibiting the retrieval of active avoidance reflex and facilitating its extinction. The data obtained show the dependence of 5-HT effect on reinforcing and triggering properties of spatial-environmental and phasic conditioned stimuli. It is suggested that intrahippocampal 5-HT administration was responsible for the retrieval of traces of conditioned reinforced stimuli.
已经确定,以2微克的剂量双侧海马内注射5-羟色胺(5-HT)可延长被动回避反射保持的时间,抑制主动回避反射的恢复并促进其消退。所获得的数据表明5-HT效应依赖于空间环境和相位条件刺激的强化和触发特性。有人提出,海马内注射5-HT是导致条件强化刺激痕迹恢复的原因。