Zielińska Magdalena, Michońska Izabela
Institute of Health Sciences, College of Medical Sciences, University of Rzeszow, Poland.
Postep Psychiatr Neurol. 2022 Sep;31(3):128-137. doi: 10.5114/ppn.2022.121730. Epub 2022 Nov 29.
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system in which multifocal damage to the brain and spinal cord occurs. The etiology of MS remains unclear but it is often recognized by researchers as a multifactorial disease that involves autoimmune and genetic predisposition combined with environmental influences (e.g., low vitamin D levels, smoking, obesity). An adequate and balanced diet can be extremely helpful in improving the condition of MS patients, effectively supporting pharmacological therapy. The purpose of the study was to investigate whether, and if so, to what extent, the intake of macronutrients, vitamins, and microelements may affect the course of MS.
The review presents data from studies published between 2017 and 2022.
There are numerous studies on the role of specific dietary components in the treatment of MS, but the results are still limited. More work is needed to define the tools required for the assessment of patients' eating habits because dietary factors can affect the functioning and quality of life of MS patients and should therefore be evaluated to assist in comprehensive treatment and recovery.
多发性硬化症(MS)是一种中枢神经系统的慢性脱髓鞘疾病,会对大脑和脊髓造成多灶性损伤。MS的病因尚不清楚,但研究人员通常认为它是一种多因素疾病,涉及自身免疫和遗传易感性,并伴有环境影响(如维生素D水平低、吸烟、肥胖)。充足且均衡的饮食对改善MS患者的病情非常有帮助,能有效辅助药物治疗。本研究的目的是调查常量营养素、维生素和微量元素的摄入是否以及在何种程度上可能影响MS的病程。
该综述展示了2017年至2022年间发表的研究数据。
关于特定饮食成分在MS治疗中的作用有大量研究,但结果仍然有限。需要开展更多工作来确定评估患者饮食习惯所需的工具,因为饮食因素会影响MS患者的功能和生活质量,因此应进行评估以辅助综合治疗和康复。