Quock R M, Kouchich F J, Tseng L F
Brain Res Bull. 1986 Mar;16(3):321-3. doi: 10.1016/0361-9230(86)90052-3.
The influence of a 60-min exposure to 75% nitrous oxide/25% oxygen upon concentrations of methionine-enkephalin-like immunoreactivity (MELI) in discrete brain regions was investigated in conscious rats. Compared to room air-exposed control animals, nitrous oxide-exposed rats had 12-18% increases in MELI in the brainstem, spinal cord, hypothalamus and corpus striatum. There were no significant differences between control and nitrous oxide-exposed rats in levels of MELI in the cerebral cortex or diencephalon.
在清醒大鼠中,研究了暴露于75%氧化亚氮/25%氧气60分钟对离散脑区中甲硫氨酸脑啡肽样免疫反应性(MELI)浓度的影响。与暴露于室内空气的对照动物相比,暴露于氧化亚氮的大鼠脑干、脊髓、下丘脑和纹状体中的MELI增加了12% - 18%。对照大鼠和暴露于氧化亚氮的大鼠在大脑皮层或间脑中的MELI水平没有显著差异。