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系统进化分析显示,2022 年 11 月在厄瓜多尔家禽中爆发的 H5N1 禽流感与高致病性 2.3.4.4b 分支有关。

Phylogenetic analysis reveals that the H5N1 avian influenza A outbreak in poultry in Ecuador in November 2022 is associated with the highly pathogenic clade 2.3.4.4b.

机构信息

Instituto Nacional de Salud Pública e Investigación "Leopoldo Izquieta-Pérez", Guayaquil, Ecuador; Universidad Agraria del Ecuador, Guayaquil, Ecuador.

Department of Clinical Biochemistry, Naestved Hospital, Naestved, Denmark; Section for Evolutionary Genomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.

出版信息

Int J Infect Dis. 2023 Aug;133:27-30. doi: 10.1016/j.ijid.2023.04.403. Epub 2023 Apr 20.

Abstract

The ongoing H5N1 outbreak in the Americas caused by clade 2.3.4.4 is causing unprecedented impact in poultry and wild birds. In November 2022, a highly pathogenic avian influenza A outbreak was declared in poultry in Ecuador, affecting more than 1.1 million heads of poultry in two farms by February 2023. Phylogenetic analysis shows that the virus clade is 2.3.4.4b, and to the best of our knowledge, this is the first scientific publication reporting this clade in South America.

摘要

在美洲由 2.3.4.4 分支引起的 H5N1 疫情正在给家禽和野生鸟类带来前所未有的影响。2022 年 11 月,厄瓜多尔的家禽中爆发了高致病性禽流感疫情,到 2023 年 2 月,两家农场的受感染家禽超过 110 万只。系统进化分析表明,该病毒属于 2.3.4.4b 分支,据我们所知,这是首次在南美洲报告该分支。

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