Yang Fei, Wei Xiaoxi, Chen Bo, Li Chenxi, Li Dong, Zhang Shugang, Lu Weigang, Zhang Lei
School of Mechanical, Electrical and Information Engineering, Shandong University, Weihai, China.
School of Computer Science and Technology, Shandong University, Qingdao, China.
Front Physiol. 2023 Apr 7;14:1086154. doi: 10.3389/fphys.2023.1086154. eCollection 2023.
The heart is a vital organ in the human body. Research and treatment for the heart have made remarkable progress, and the functional mechanisms of the heart have been simulated and rendered through the construction of relevant models. The current methods for rendering cardiac functional mechanisms only consider one type of modality, which means they cannot show how different types of modality, such as physical and physiological, work together. To realistically represent the three-dimensional synergetic biological modality of the heart, this paper proposes a WebGL-based cardiac synergetic modality rendering framework to visualize the cardiac physical volume data and present synergetic correspondence rendering of the cardiac electrophysiological modality. By constructing the biological detailed interactive histogram, users can implement local details rendering for the heart, which could reveal the cardiac biology details more clearly. We also present cardiac physical-physiological correlation visualization to explore cardiac biological association characteristics. Experimental results show that the proposed framework can provide favorable cardiac biological detailed synergetic modality rendering results in terms of both effectiveness and efficiency. Compared with existing methods, the framework can facilitate the study of the internal mechanism of the heart and subsequently deduce the process of initiation, development, and transformation from a healthy heart to an ill one, and thereby improve the diagnosis and treatment of cardiac disorders.
心脏是人体中的重要器官。心脏的研究与治疗已取得显著进展，通过构建相关模型对心脏的功能机制进行了模拟与呈现。当前呈现心脏功能机制的方法仅考虑一种模态类型，这意味着它们无法展示不同类型的模态（如物理和生理模态）是如何协同工作的。为了逼真地呈现心脏的三维协同生物模态，本文提出了一种基于WebGL的心脏协同模态渲染框架，以可视化心脏物理体积数据并呈现心脏电生理模态的协同对应渲染。通过构建生物详细交互式直方图，用户可以对心脏进行局部细节渲染，从而更清晰地揭示心脏生物学细节。我们还展示了心脏物理 - 生理相关性可视化，以探索心脏生物关联特征。实验结果表明，所提出的框架在有效性和效率方面都能提供良好的心脏生物详细协同模态渲染结果。与现有方法相比，该框架有助于研究心脏的内部机制，进而推断从健康心脏到患病心脏的起始、发展和转变过程，从而改善心脏疾病的诊断和治疗。
