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使用数字血压指导仪进行家庭血压监测期间的血压动态变化——个体用户数据的前瞻性分析

Blood pressure dynamics during home blood pressure monitoring with a digital blood pressure coach-a prospective analysis of individual user data.

作者信息

Beger Christian, Rüegger Dominik, Lenz Anna, Wagner Steffen, Haller Herrmann, Schmidt-Ott Kai Martin, Volland Dirk, Limbourg Florian P

机构信息

Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.

Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.

出版信息

Front Cardiovasc Med. 2023 Apr 5;10:1115987. doi: 10.3389/fcvm.2023.1115987. eCollection 2023.

Abstract

INTRODUCTION

Self-monitoring of blood pressure at home is a better predictor of prognosis and recommended in hypertension guidelines. However, the influence of baseline blood pressure category and measurement schedule on BP values during a period of home blood pressure monitoring (HBPM) are still poorly defined, particularly when used in conjunction with a digital application.

METHODS

We analysed temporal BP changes and performed BP classification tracking in users with self-reported hypertension performing HBPM with a digital and interactive blood pressure coach.

RESULTS

Of 3175 users who enrolled in HBPM, 74.1% completed the first measurement period. Overall, mean systolic BP dropped significantly after the first day, but stratification by BP category demonstrated that initial category influenced BP course. BP classification tracking revealed that time to reach final BP category was dependent on baseline category, with users in categories high normal and grade 1 hypertension requiring more days to decrease BP class volatility and to reach their definitive BP class. This was driven by an intense switching between directly neighbouring categories until the middle phase of the HBPM period, while more distant class switching occurred less often and only early on. Overall, >90% of users maintained their category by day 5. Omitting the first day from analysis lead to therapeutically relevant reclassification in 3.8% of users. Users who completed at least two HBPM periods ( = 864) showed a mean SBP/DBP decrease of 2.6/1.6 mmHg, which improved hypertension control from 55.6% to 68.1%.

CONCLUSION

The optimal length of HBPM period depends on BP category. HBPM with a digital coach is associated with a reduction in average BP and improvement in BP control.

摘要

引言

家庭血压自我监测能更好地预测预后,高血压指南中也推荐使用。然而,在家庭血压监测(HBPM)期间,基线血压类别和测量方案对血压值的影响仍未明确,尤其是与数字应用程序结合使用时。

方法

我们分析了自我报告患有高血压的用户在使用数字交互式血压指导仪进行HBPM期间的血压随时间变化情况,并进行了血压分类跟踪。

结果

在3175名参与HBPM的用户中,74.1%完成了第一个测量周期。总体而言,第一天后平均收缩压显著下降,但按血压类别分层显示,初始类别会影响血压变化过程。血压分类跟踪显示,达到最终血压类别的时间取决于基线类别,高正常血压和1级高血压类别的用户需要更多天数来降低血压类别波动并达到其确定的血压类别。这是由于在HBPM期间的中期之前,直接相邻类别之间频繁切换,而较远类别之间的切换较少且仅在早期发生。总体而言,超过90%的用户在第5天时维持了其类别。分析中省略第一天导致3.8%的用户出现与治疗相关的重新分类。完成至少两个HBPM周期(n = 864)的用户平均收缩压/舒张压下降了2.6/1.6 mmHg,高血压控制率从55.6%提高到68.1%。

结论

HBPM周期的最佳长度取决于血压类别。使用数字指导仪进行HBPM与平均血压降低和血压控制改善相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1263/10113611/9e2d0c5c4793/fcvm-10-1115987-g001.jpg

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