Al-Nahrain University, Baghdad, Iraq.
Ibn Al-Bitar Specialized Center for Cardiac Surgery, Baghdad, Iraq.
Biomed Res Int. 2023 Apr 12;2023:2721427. doi: 10.1155/2023/2721427. eCollection 2023.
One of the primary indicators of plaque vulnerability is the lipid composition of atherosclerotic plaques. Therefore, the medical industry requires a method to evaluate necrotic nuclei in atherosclerosis imaging with sensitivity. In this regard, photoacoustic imaging is a plaque detection method that provides chemical information on lipids and cholesterol thickness in the arterial walls of the patient. This aspect aims to increase the low-frequency axial resolution by developing a new photoacoustic-based system. A photoacoustic system has been developed to detect the cholesterol thickness of the blood vessels to observe the progression of plaque in the heart's blood vessels. The application of the coherent photoacoustic discontinuous correlation tomography technique, which is based on a novel signal processing, significantly increased the cholesterol oleate's sensitivity to plaque necrosis. By enhancing the quality of thickness detection, the system for measuring the thickness of cholesterol in blood vessels has been reduced to approximately 23 microns. The results show that the phase spectrum peaked at 100 Hz at 58.66 degrees, and at 400 Hz, the phase spectrum was 46.37 degrees. The minimum amplitude is 1.95 at 100 Hz and 17.67 at 400 Hz. In conclusion, it can be stated that photoacoustic imaging as a method based on new technologies is of great importance in medical research, which is based on the use of nonionizing radiation to perform diagnostic processes and measure different types of body tissues.
斑块易损性的一个主要指标是动脉粥样硬化斑块的脂质组成。因此，医学界需要一种方法来评估动脉粥样硬化成像中坏死核的敏感性。在这方面，光声成像是一种斑块检测方法，可提供患者动脉壁中脂质和胆固醇厚度的化学信息。这方面的目的是通过开发新的基于光声的系统来提高低频轴向分辨率。已经开发了一种光声系统来检测血管的胆固醇厚度，以观察心脏血管中斑块的进展。相干光声不连续相关断层成像技术的应用，基于一种新的信号处理，显著提高了胆固醇油酸对斑块坏死的灵敏度。通过提高厚度检测的质量，血管中胆固醇厚度的测量系统已降低到约 23 微米。结果表明，相位谱在 58.66 度处以 100 Hz 为峰值，在 400 Hz 处，相位谱为 46.37 度。在 100 Hz 时最小幅度为 1.95，在 400 Hz 时最小幅度为 17.67。总之，可以说，基于新技术的光声成像是医学研究中非常重要的方法，它基于使用非电离辐射来进行诊断过程并测量不同类型的身体组织。
