Parmar Mihirkumar P, Kathal Ritik, Bhavanam Sravani, Baskaran Pranaya, Varsaale Nayanaa, Padamati Bhavani, Bhuchakra Hamsa Priya, C Mohammed Faseel, Sahu Sweta, Davalgi Shubha
Internal Medicine, GMERS Medical College and Hospital, Vadnagar, IND.
Internal Medicine, Shyam Shah Medical College, Rewa, IND.
Cureus. 2023 Mar 20;15(3):e36388. doi: 10.7759/cureus.36388. eCollection 2023 Mar.
Coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed millions of people around the world so far and has turned into a disaster for people and healthcare systems. Neurological problems are often seen in people with COVID-19 in the general population, but it is unclear how common they are in pregnant women. This study provides a summary of studies on pregnant women with proven SARS-CoV-2 infection and a particular neurologic diagnosis from different parts of the world. After applying the inclusion and exclusion criteria, a total of 15 papers were assessed to create this review article. Based on our findings, the peripheral and central nervous systems were both equally impacted: Guillain-Barré syndrome (GBS, n=1), bifacial weakness, paresthesia, and vestibulocochlear neuritis (n=1), eclampsia types (n=2), and neurological disease (n=2); case reports, retrospective studies, editorials, and prospective observational studies were included. The median gestational age was 34 (30-36.5) weeks, and the median maternal age was 32.5 (25-35) years. Given the number of reports of neurologic problems associated with COVID-19 in the general community, our findings might be overstated, and we chose the ones that fit our criteria. We hope that this review helps in the early detection and management of neurological diseases during pregnancy.
2019冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,迄今为止已导致全球数百万人死亡,并给人类和医疗系统带来了一场灾难。在普通人群中,COVID-19患者常出现神经问题,但在孕妇中这些问题的普遍程度尚不清楚。本研究总结了世界各地关于确诊感染SARS-CoV-2且患有特定神经疾病的孕妇的研究。在应用纳入和排除标准后,共评估了15篇论文以撰写本综述文章。根据我们的研究结果,外周神经系统和中枢神经系统均受到同等程度的影响:吉兰-巴雷综合征(GBS,n = 1)、双侧面瘫、感觉异常和前庭蜗神经炎(n = 1)、子痫类型(n = 2)以及神经疾病(n = 2);纳入了病例报告、回顾性研究、社论和前瞻性观察性研究。中位孕周为34(30 - 36.5)周,中位产妇年龄为32.5(25 - 35)岁。鉴于普通社区中与COVID-19相关的神经问题报告数量,我们的研究结果可能有所夸大,我们选择了符合我们标准的报告。我们希望本综述有助于孕期神经疾病的早期检测和管理。