氯沙坦诱发血管性水肿的病例报告。
A Case Report of Losartan Induced Angioedema.
作者信息
Vedantam Venkata, Magacha Hezborn M, Vedantam Neethu, Dahya Vanessa, Abu-Heija Usama
机构信息
Internal Medicine, East Tennessee State University - Quillen College of Medicine, Johnson City, USA.
General Practice, East Tennessee State University, Johnson City, USA.
出版信息
Cureus. 2023 Mar 22;15(3):e36525. doi: 10.7759/cureus.36525. eCollection 2023 Mar.
Abstract
Angiotensin-converting-enzyme inhibitors (ACEI) and Angiotensin Receptor Blockers (ARBs) are commonly used to manage hypertension and cardiovascular diseases. Although angioedema due to ACEI is a well-known side effect, only a few cases are associated with ARBs, such as losartan. Medication-induced angioedema has been known for many years; however, the mechanism by which many medications cause angioedema is not clearly understood. Here we present the case of angioedema in a 50-year-old male taking losartan after he developed acute kidney disease.
摘要
血管紧张素转换酶抑制剂（ACEI）和血管紧张素受体阻滞剂（ARBs）常用于治疗高血压和心血管疾病。虽然ACEI引起的血管性水肿是一种众所周知的副作用，但只有少数病例与ARBs（如氯沙坦）有关。药物性血管性水肿已为人所知多年；然而，许多药物导致血管性水肿的机制尚不清楚。在此，我们报告一例50岁男性在患急性肾病后服用氯沙坦出现血管性水肿的病例。
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