Nehme Antonio, Barakat Muna, Malaeb Diana, Obeid Sahar, Hallit Souheil, Haddad Georges
School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon.
Department of Clinical Pharmacy and therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, 11931, Jordan.
Pharm Pract (Granada). 2023 Jan-Mar;21(1):2763. doi: 10.18549/PharmPract.2023.1.2763. Epub 2022 Dec 21.
Long COVID syndrome, the poorly defined illness, has been increasingly mentioned in recent studies yet is still poorly understood especially when it comes to precipitating and modulating factors, the high prevalence of mental health problems associated with the COVID-19 pandemic has brought to light the hypothesis of the existence of a psychological component associated with the persistence of symptoms and if vaccination may serve as a modulating factor. This study aims to examine the prevalence of somatization disorders and association between persistent COVID-19 symptoms and COVID-19 vaccine with somatization among a sample of the Lebanese general population.
A cross-sectional study was carried out between September and October 2021. The snowball sampling technique was picked to choose a sample that addressed all Lebanese Mohafazat. Patient Health Questionnaire-15 (PHQ-15) was used to assess somatization.
A total of 403 participants was enrolled in this study, with a mean age of 32.76 ± 13.24 years, 108 (26.8%) had medium somatization symptoms (PHQ-15 scores ≥10). Having persistent COVID symptoms (β=2.15) was significantly associated with more somatization, whereas the intake of COVID vaccine (β=-1.17) was significantly associated with less somatization.
Long lasting COVID-19 symptoms were closely related to somatization, although the administration of the COVID-19 vaccine was associated with less somatization. However, further studies are needed to provide a better understanding of the relationship between long COVID and somatization, on one hand, and the modulating factors on the other hand.
长新冠综合征是一种定义尚不明确的疾病,在最近的研究中被越来越多地提及,但人们对其仍知之甚少,尤其是在诱发和调节因素方面。与新冠疫情相关的心理健康问题的高患病率引发了一种假设,即存在与症状持续存在相关的心理成分,以及疫苗接种是否可能作为一种调节因素。本研究旨在调查黎巴嫩普通人群样本中躯体化障碍的患病率,以及持续的新冠症状和新冠疫苗与躯体化之间的关联。
于2021年9月至10月进行了一项横断面研究。采用滚雪球抽样技术选择一个涵盖黎巴嫩所有省份的样本。使用患者健康问卷-15(PHQ-15)评估躯体化情况。
本研究共纳入403名参与者,平均年龄为32.76±13.24岁,108人(26.8%)有中度躯体化症状(PHQ-15评分≥10)。有持续新冠症状(β=2.15)与更多的躯体化显著相关,而接种新冠疫苗(β=-1.17)与较少的躯体化显著相关。
长期的新冠症状与躯体化密切相关,尽管接种新冠疫苗与较少的躯体化有关。然而,一方面需要进一步研究以更好地理解长新冠与躯体化之间的关系,另一方面也需要研究调节因素。