Suppr超能文献

FishGET:一个具有更高准确性和可视化效果的鱼类基因表达与转录组数据库。

FishGET: A fish gene expression and transcriptome database with improved accuracy and visualization.

作者信息

Guo Cheng, Duan You, Ye Weidong, Zhang Wanting, Cheng Yingyin, Shi Mijuan, Xia Xiao-Qin

机构信息

Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.

College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, China.

出版信息

iScience. 2023 Mar 31;26(4):106539. doi: 10.1016/j.isci.2023.106539. eCollection 2023 Apr 21.

Abstract

With the rapid expansion of transcriptome studies in many fishes, a great number of RNA-seq data have been published, allowing for a more systematic understanding of the general profiles and details of gene expression in fish. FishGET is dedicated to gathering and curating fish RNA-seq data to discover more new RNAs, including mRNA and lncRNA, thereby getting a more complete reference transcriptome and providing more comprehensive and accurate transcriptome annotations. We obtained a total of 1362 RNA-seq paired-end data of 8 fishes from 97 different studies, and then we performed transcript assembly, meta-assembly, weighted gene co-expression network analysis (WGCNA), functional annotations, neighbor location annotation, lncRNA type annotation, homology annotation. To promote research into fish genes at the transcriptional level, we developed a user-friendly web interface that allows users to view all information and makes use of multiple types of dynamic interactive visualization services.

摘要

随着许多鱼类转录组研究的迅速扩展,大量RNA测序数据已被发表,这使得人们能够更系统地了解鱼类基因表达的总体概况和细节。FishGET致力于收集和整理鱼类RNA测序数据,以发现更多新的RNA,包括mRNA和lncRNA,从而获得更完整的参考转录组,并提供更全面、准确的转录组注释。我们从97项不同研究中总共获得了8种鱼类的1362个RNA测序双端数据,然后进行了转录本组装、元组装、加权基因共表达网络分析(WGCNA)、功能注释、邻位定位注释、lncRNA类型注释、同源性注释。为了促进鱼类基因在转录水平上的研究,我们开发了一个用户友好的网络界面,该界面允许用户查看所有信息,并利用多种类型的动态交互式可视化服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/575b/10119798/d5a412a59120/fx1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验