Bohac Maja, Biscevic Alma, Ahmedbegovic-Pjano Melisa, Jagic Mateja, Gabric Doria, Lukacevic Selma, Mravicic Ivana
University Eye Hospital Svjetlost, School of Medicine University of Rijeka, Zagreb, Croatia.
Eye Clinic Svjetlost, Sarajevo, Bosnia and Herzegovina.
Mater Sociomed. 2023 Mar;35(1):73-78. doi: 10.5455/msm.2023.35.73-78.
Corneal ectasia is a sight-threatening complication of corneal refractive surgery characterized by progressive steepening and thinning of the cornea and subsequent loss of best-corrected visual acuity.
To report the clinical outcomes following treatment of post-laser in situ keratomileusis (LASIK) induced ectasia.
This is a retrospective case series of 7 patients (10 eyes) which developed post-LASIK ectasia. In these cases of postoperative ectasia, the presented clinical signs were either forme fruste keratoconus, thin cornea, posterior elevation map value > +15.0µm, or residual stromal bed < 300µm. All cases were treated with either collagen crosslinking (CXL) alone or combined with PRK or CXL and phakic intraocular implant using the Dresden protocol and a slight modification thereof. In all cases, the flap was created using the Moria M2 mechanical microkeratome (average flap thickness 118.15±12.88µm), and refractive error was corrected using the Wavelight Allegretto excimer laser.
Average preoperative corrected visual acuity (CDVA) was 0.75 (±0.26) Snellen. Postoperative CDVA significantly increased to 0.86 (±0.13) Snellen (p=0.04, paired t-test). One eye lost three lines of its baseline CDVA (before ectasia), while all other eyes regained lines of CDVA. All cases remained stable during the follow-up.
Several surgical procedures are used for the management of corneal ectasia. However, the best surgical approach should be determined based on the state of progression of the disease. Although ectasia remains a potentially devastating complication after refractive surgery, most patients can regain functional visual acuity with appropriate management, and corneal transplantation is infrequently indicated.
角膜扩张是角膜屈光手术一种威胁视力的并发症,其特征为角膜逐渐变陡、变薄,随后最佳矫正视力下降。
报告准分子原位角膜磨镶术(LASIK)后发生角膜扩张的治疗临床结果。
这是一项回顾性病例系列研究,纳入7例(10只眼)发生LASIK术后角膜扩张的患者。在这些术后角膜扩张病例中,呈现的临床体征为顿挫型圆锥角膜、角膜变薄、后表面高度图值>+15.0µm或剩余基质床<300µm。所有病例均采用德累斯顿方案及其轻微改良方案,单独使用胶原交联(CXL)或联合准分子激光角膜切削术(PRK),或CXL与有晶状体眼人工晶状体植入术进行治疗。所有病例均使用Moria M2机械微型角膜刀制作角膜瓣(平均角膜瓣厚度118.15±12.88µm),并使用鹰视准分子激光矫正屈光不正。
术前平均矫正视力(CDVA)为0.75(±0.26)(Snellen视力表)。术后CDVA显著提高至0.86(±0.13)(Snellen视力表)(p=0.04,配对t检验)。1只眼的基线CDVA(角膜扩张前)下降了3行,而所有其他眼的CDVA均有所恢复。所有病例在随访期间均保持稳定。
有多种手术方法用于治疗角膜扩张。然而,最佳手术方法应根据疾病的进展情况来确定。虽然角膜扩张仍然是屈光手术后一种潜在的严重并发症,但大多数患者通过适当的治疗可以恢复功能性视力,很少需要进行角膜移植。