Kırıkkale University,Education Faculty, Department Of Mathematics and Science Education, Science Education, /Kırıkkale, 71450, Yahşihan, Turkey.
J Chem Ecol. 2023 Jun;49(5-6):230-234. doi: 10.1007/s10886-023-01421-6. Epub 2023 Apr 25.
The importance of finding natural solutions for the protection of our health in the fight against pests in agriculture is increasing day by day. In this study, the interaction of the active ingredients in marigolds as the great importance as a garden flower, with nematode and whitefly receptors as ligands in the fight against them, have been investigated by chemical calculation method. The inhibition effect of ligands (alpha-Terthienyl, Quercetagetin in marigold) on nematode and whitefly receptors in this plant was determined by comparing the binding energy values with reference drug active ingredients (imidacloprid, Perhexiline).This calculation method, the accuracy determined by different studies, is very important in terms of determining the most active substance in a short time, preventing time and substance loss, and will guide the experimental studies and applications to be made in this field.
寻找天然解决方案以保护我们的健康，在农业中对抗害虫的重要性日益增加。在这项研究中，通过化学计算方法研究了万寿菊作为花园花卉的重要活性成分与线虫和粉虱受体的相互作用，作为配体与之对抗。通过比较结合能值与参考药物活性成分（噻虫啉、栎精），确定了配体（α-噻吩、万寿菊中的槲皮素）对线虫和粉虱受体的抑制作用。该计算方法的准确性已通过不同研究确定，在短时间内确定最有效物质、防止时间和物质损失方面非常重要，并将指导该领域的实验研究和应用。
