Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, 30322, USA.
Department of Gynecology and Obstetrics, Emory University, 1365 E Clifton Rd NE, Atlanta, GA, 30322, USA.
J Autism Dev Disord. 2024 Jun;54(6):2355-2367. doi: 10.1007/s10803-023-05982-z. Epub 2023 Apr 25.
Prenatal cannabis use and maternal stress have been proposed as risk factors for autism spectrum disorder (ASD). Black mothers and mothers of lower socioeconomic status (SES) may be especially likely to experience high levels of stress. This study examined the impact of prenatal cannabis use and maternal stress (i.e., prenatal distress, racial discrimination, and lower SES) on child ASD-related behaviors in a sample of 172 Black mother-child pairs. We found that prenatal stress was significantly associated with ASD-related behaviors. Prenatal cannabis use did not predict ASD-related behaviors and did not interact with maternal stress to predict ASD-related behaviors. These findings replicate previous work on prenatal stress-ASD associations and add to the limited literature on prenatal cannabis-ASD associations in Black samples.
产前使用大麻和产妇压力被认为是自闭症谱系障碍（ASD）的风险因素。黑人和社会经济地位较低的母亲可能特别容易经历高水平的压力。本研究在 172 对黑人和儿童样本中，考察了产前使用大麻和产妇压力（即产前焦虑、种族歧视和社会经济地位较低）对儿童 ASD 相关行为的影响。我们发现，产前压力与 ASD 相关行为显著相关。产前使用大麻并不能预测 ASD 相关行为，也不能与产妇压力相互作用来预测 ASD 相关行为。这些发现复制了之前关于产前压力与 ASD 关联的研究，也增加了关于黑人样本中产前使用大麻与 ASD 关联的有限文献。
