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曲折而混乱:空气污染对眼部健康影响的系统评价

Meandered and muddled: a systematic review on the impact of air pollution on ocular health.

作者信息

Muruganandam Niveditha, Mahalingam Sneha, Narayanan Ramsundram, Rajadurai Elangovan

机构信息

Department of Civil Engineering, Kumaraguru College of Technology, Anna University, Coimbatore, Tamil Nadu, India.

Department of Civil Engineering, Kumaraguru College of Technology, Coimbatore, Tamil Nadu, India.

出版信息

Environ Sci Pollut Res Int. 2023 May;30(24):64872-64890. doi: 10.1007/s11356-023-27079-x. Epub 2023 Apr 25.

DOI:10.1007/s11356-023-27079-x
PMID:37097565
Abstract

From the years 1970-2023, a systematic overview of the diverse consequences of particulate matter on eye health and a disease classification according to acute, chronic, and genetic are presented using the PubMed, Research Gate, Google Scholar, and Science Direct databases. Various studies on medical aspects correlate with the eye and health. However, from an application perspective, there is limited research on the ocular surface and air pollution. The main objective of the study is to uncover the relationship between eye health and air pollution, particularly particulate matter, along with other external factors acting as aggravators. The secondary goal of the work is to examine the existing models for mimicking human eyes. The study is followed by a questionnaire survey in a workshop, in which the exposure-based investigation was tagged based on their activity. This paper establishes a relationship between particulate matter and its influence on human health, leading to numerous eye diseases like dry eyes, conjunctivitis, myopia, glaucoma, and trachoma. The results of the questionnaire survey indicate that about 68% of the people working in the workshop are symptomatic with tears, blurred vision, and mood swings, while 32% of the people were asymptomatic. Although there are approaches for conducting experiments, the evaluation is not well defined; empirical and numerical solutions for particle deposition on the eye are needed. There prevails a broad gap in the arena of ocular deposition modeling.

摘要

从1970年至2023年,利用PubMed、Research Gate、谷歌学术和科学Direct数据库,对颗粒物对眼部健康的各种影响进行了系统综述,并根据急性、慢性和遗传因素进行了疾病分类。关于医学方面的各种研究与眼睛和健康相关。然而,从应用角度来看,关于眼表与空气污染的研究有限。该研究的主要目的是揭示眼睛健康与空气污染,特别是颗粒物之间的关系,以及其他作为加重因素的外部因素。这项工作的次要目标是研究现有的模拟人眼的模型。该研究之后在一个研讨会上进行了问卷调查,其中基于活动对基于暴露的调查进行了标记。本文建立了颗粒物与其对人类健康的影响之间的关系,这种影响会导致许多眼部疾病,如干眼症、结膜炎、近视、青光眼和沙眼。问卷调查结果表明,在研讨会上工作的人中约68%有流泪、视力模糊和情绪波动等症状,而32%的人没有症状。虽然有进行实验的方法,但评估并不明确;需要关于颗粒在眼睛上沉积的经验和数值解决方案。在眼部沉积建模领域存在很大差距。

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引用本文的文献

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Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence.颗粒物与空气污染对眼表疾病的影响:临床前和临床证据的系统评价
Ocul Surf. 2025 Jan;35:100-116. doi: 10.1016/j.jtos.2024.12.003. Epub 2024 Dec 12.
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Association Between Particulate Matter Pollutants and Ophthalmology Visits for Ocular Surface Irritation and Allergy.颗粒物污染物与因眼表刺激和过敏而进行眼科就诊之间的关联。
Clin Ophthalmol. 2024 Nov 13;18:3263-3270. doi: 10.2147/OPTH.S485199. eCollection 2024.
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Enhanced Intrusion of Exogenous Airborne Fine Particles toward Eyes in Humans and Animals: Where Damaged Blood-Ocular Barrier Plays a Crucial Role.
增强的外源性空气细颗粒物向人和动物眼睛的侵入:受损的血眼屏障起着关键作用。
Environ Sci Technol. 2024 Aug 6;58(31):13636-13647. doi: 10.1021/acs.est.4c01791. Epub 2024 Jul 3.