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Activity-induced thermogenesis in lean and genetically obese (ob/ob) mice.

作者信息

Dauncey M J

出版信息

Experientia. 1986 May 15;42(5):547-9. doi: 10.1007/BF01946696.

DOI:10.1007/BF01946696
PMID:3709761
Abstract

Motor activity was approximately 60% lower in genetically obese than in lean mice, during three consecutive hours at thermal neutrality. It is suggested that this must have contributed to the lower heat production measured in the obese mice and that activity-induced thermogenesis contributes significantly to differences in energy expenditure between the genotypes, at least in the short-term.

摘要

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Leptin signaling is required for adaptive changes in food intake, but not energy expenditure, in response to different thermal conditions.瘦素信号传导是不同热条件下食物摄入量适应性变化所必需的,但不是能量消耗所必需的。
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Central nervous control of energy and glucose balance: focus on the central melanocortin system.中枢神经系统对能量和葡萄糖平衡的控制:关注中枢黑皮质素系统。
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Identification of a physiological role for leptin in the regulation of ambulatory activity and wheel running in mice.鉴定瘦素在调节小鼠活动和轮跑中的生理作用。
Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E392-401. doi: 10.1152/ajpendo.00546.2010. Epub 2010 Nov 9.
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Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity.高基础有氧能力选育大鼠的自发性活动、活动经济性和抵抗饮食诱导肥胖的能力。
Horm Behav. 2010 Aug;58(3):355-67. doi: 10.1016/j.yhbeh.2010.03.013. Epub 2010 Mar 27.
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Acute administration of leptin produces anxiolytic-like effects: a comparison with fluoxetine.急性给予瘦素可产生抗焦虑样作用:与氟西汀的比较。
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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion.瘦素受体调节的神经元在控制新陈代谢和摄食方面的集体和个体功能。
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