Basova N A, Kushak R I
Fiziol Zh SSSR Im I M Sechenova. 1986 Apr;72(4):520-7.
Absorption of free and peptide glycine released at the hydrolysis of glycyl-L-leucine, L-leucyl-glycine, glycyl-L-valine was investigated in experiments in vitro with accumulating mucosal preparations of the chick small intestine. An active accumulation of free amino acid occurred in the mucosa depending on sodium and oxygen presence in the incubation medium. The participation of sodium-dependent and sodium-independent components in the transport was revealed. Absorption of peptide glycine released at the hydrolysis of glycyl-L-leucine and glycyl-L-valine appeared to be a sodium-independent process and demanded the energy of aerobic metabolism. The data indicate the effect of various amino acids on the transport of free and peptide glycine. Activating effect of some of them on the absorption of glycine is supposed to be determined for this amino acid by a mechanism of exchange transport in the chick small intestine.
利用雏鸡小肠黏膜累积制剂进行体外实验，研究了甘氨酰 -L-亮氨酸、L-亮氨酰 -甘氨酸、甘氨酰 -L-缬氨酸水解时释放的游离甘氨酸和肽甘氨酸的吸收情况。黏膜中出现了游离氨基酸的主动累积，这取决于孵育介质中钠和氧的存在。揭示了钠依赖性和非钠依赖性成分在转运中的参与情况。甘氨酰 -L-亮氨酸和甘氨酰 -L-缬氨酸水解时释放的肽甘氨酸的吸收似乎是一个非钠依赖性过程，需要有氧代谢的能量。数据表明了各种氨基酸对游离甘氨酸和肽甘氨酸转运的影响。推测其中一些氨基酸对甘氨酸吸收的激活作用是通过雏鸡小肠中的交换转运机制来确定这种氨基酸的。
