[Dynamics of morpho-functional changes in gastrin-producing cells of the stomach after electric stimulation of the vagus nerve].

In 25 white rats, direct stimulation of the vagus nerve increased the average diameter of secretory granules and decreased their number and volume, thus reflecting the release of gastrin during first 5 min after the stimulation. Subsequent increase in volume of nucleus, nucleolus, endoplasmatic reticulum, mitochondria and Golgi complex suggest rapid activation of hormone synthesis in G cells under vagostimulation. The data obtained allow to revise the existing concepts of gastrin release from cells and of ultrastructural criteria of this process.