Ministry of Health Ankara City Hospital, Emergency Medicine Department - Ankara, Turkey.
Ankara Yıldırım Beyazıt Üniversitesi, Faculty of Medicine, Emergency Medicine - Ankara, Turkey.
Rev Assoc Med Bras (1992). 2023 Apr 21;69(4):e20221185. doi: 10.1590/1806-9282.20221185. eCollection 2023.
Mechanical damage resulting from aortic dissection creates a thrombus in the false lumen, in which platelets are involved. Platelet index is useful for the function and activation of platelets. The aim of this study was to show the clinical relevance of the platelet index of aortic dissection.
A total of 88 patients diagnosed with aortic dissection were included in this retrospective study. Demographic data and hemogram and biochemistry results of the patients were determined. Patients were divided into two groups: deceased and surviving patients. The data obtained were compared with 30-day mortality. The primary outcome was the relationship of platelet index with mortality.
A total of 88 patients, 22 of whom were female (25.0%), diagnosed with aortic dissection, were included in the study. It was determined that 27 (30.7%) of the patients were mortal. The mean age of the entire patient group was 58±13 years. According to the DeBakey classification of aortic dissection of the patients, the percentages of the 1-2-3 type were determined as 61.4, 8.0, and 30.7%, respectively. Platelet index was not found to be directly related to mortality. Increase in age, decrease in bicarbonate value, and presence of diabetes mellitus were associated with mortality.
Although there were no significant changes in platelet index in aortic dissection, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were found to be high in line with the literature. In particular, the presence of advanced age diabetes mellitus and decrease in bicarbonate are associated with mortality.
主动脉夹层导致的机械损伤会在假腔中形成血栓，其中血小板参与其中。血小板指数可用于评估血小板的功能和激活状态。本研究旨在展示主动脉夹层血小板指数的临床相关性。
回顾性纳入 88 例主动脉夹层患者，记录患者的人口统计学数据、血常规和生化结果。根据患者的预后分为死亡组和存活组，比较两组间血小板指数与 30 天死亡率的关系。主要结局是血小板指数与死亡率的关系。
共纳入 88 例主动脉夹层患者，其中女性 22 例（25.0%），平均年龄（58±13）岁。根据主动脉夹层的 DeBakey 分型，1 型、2 型和 3 型患者分别占 61.4%、8.0%和 30.7%。血小板指数与死亡率无直接相关性。高龄、碳酸氢盐降低和糖尿病与死亡率相关。
尽管主动脉夹层患者的血小板指数无明显变化，但中性粒细胞/淋巴细胞比值和血小板/淋巴细胞比值与文献报道一致，均升高。高龄、糖尿病和碳酸氢盐降低与死亡率相关。
